[{"idx":91638,"drug_code":"2019031300009","drug_name":"\uC548\uAD6D\uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uCEA1\uC29030mg","drug_enm":"Ahngook Oseltamivir Cap. 30mg","noins":null,"narcotic_kind_code":" ","list_sunb_name":"Oseltamivir Phosphate 39.4mg","cls_code_num":"629","sunb":"Oseltamivir Phosphate\u3000\uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC778\uC0B0\uC5FC\u300039.4mg (\uC624\uC140\uD0C0\uBBF8\uBE44\uB974(\uC73C)\uB85C\uC11C 30mg)<\/a>@","drug_cls":"1","sunb_count":1,"upso_name":"\uC548\uAD6D\uC57D\uD488|Ahn-Gook Pharm|(150-823) \uC11C\uC6B8\uD2B9\uBCC4\uC2DC \uC601\uB4F1\uD3EC\uAD6C \uC2DC\uD765\uB300\uB85C 613|02) 3289-4200|02) 849-4124|http:\/\/www.ahn-gook.com","upso1":"","drug_form":"\uACBD\uC9C8\uCEA1\uC290","dosage_route":"\uACBD\uAD6C(\uB0B4\uC6A9\uACE0\uD615)","charact":"\uD770\uC0C9 \uB610\uB294 \uC5F0\uD55C \uB178\uB780\uC0C9\uC758 \uAC00\uB8E8\uAC00 \uB4E0 \uC0C1\uD558\uBD80 \uC5F0\uD55C \uB178\uB780\uC0C9\uC758 \uACBD\uC9C8\uCEA1\uC290","charact_new":"\uD770\uC0C9 \uB610\uB294 \uC5F0\uD55C \uB178\uB780\uC0C9\uC758 \uAC00\uB8E8\uAC00 \uB4E0 \uC0C1\uD558\uBD80 \uC5F0\uD55C \uB178\uB780\uC0C9\uC758 \uACBD\uC9C8\uCEA1\uC290","cls_code":"\uAE30\uD0C0\uC758 \uD654\uD559\uC694\uBC95\uC81C","atc_cd":"J05AH02|OSELTAMIVIR|\uC624\uC140\uD0C0\uBBF8\uBE44\uB974","boh_history":"650205070|854\uC6D0\/1\uCEA1\uC290 \uAE09\uC5EC (2019-06-01)^650205070|\uC6D0\/1\uCEA1\uC290 \uC0AD\uC81C (2022-11-01)","boh_hiracode":"650205070","item_permit_date":"20190312","cancel_date":"20240312","newdrug_class_code":"N","bioeq_prodt_yn":"N","comp_drug_yn_biology":"N","comp_drug_yn_effect":"N","comp_drug_yn":"N","comp_drug_yn_physicochemical":"N","kpic_atc":"Oseltamivir Phosphate : \uAC10\uC5FC\uC131\uC9C8\uD658<\/a> > \uD56D\uBC14\uC774\uB7EC\uC2A4\uC81C<\/a> > \uD56D\uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4<\/a>","kpic_atc_cd":"A02BA01","insertpaper":"","paper_dt":"","dur_age":"","dur_contra":"","dur_preg":"","dur_senior":"","dur_dose":"","dur_period":"","dur_donate":"","dur_form":"","fdacode":"C","fdacontent":"C \uB4F1\uAE09 : \uD0DC\uC544\uC5D0 \uB300\uD55C \uC704\uD5D8\uC131\uC744 \uC644\uC804\uD788 \uBC30\uC81C\uD560 \uC218 \uC5C6\uC74C. 1) \uC0AC\uB78C\uACFC \uB3D9\uBB3C \uBAA8\uB450\uC5D0\uC11C \uC801\uC808\uD558\uACE0 \uC798 \uD1B5\uC81C\uB41C \uC5F0\uAD6C \uC790\uB8CC\uAC00 \uC5C6\uB294 \uACBD\uC6B0. \uB610\uB294, 2) \uC0AC\uB78C\uC5D0 \uB300\uD574 \uC801\uC808\uD558\uACE0 \uC798 \uD1B5\uC81C\uB41C \uC5F0\uAD6C \uC790\uB8CC\uB294 \uC5C6\uC73C\uB098, \uB3D9\uBB3C\uC5D0 \uB300\uD55C \uC5F0\uAD6C \uACB0\uACFC \uD0DC\uC790\uC5D0 \uB300\uD55C \uC704\uD5D8\uC131\uC774 \uB098\uD0C0\uB09C \uACBD\uC6B0. \uD574\uB2F9 \uC57D\uBB3C\uC774 \uC784\uBD80\uC5D0\uAC8C \uD22C\uC5EC\uB420 \uACBD\uC6B0 \uD0DC\uC544\uC5D0\uAC8C \uC704\uD5D8\uD560 \uAC00\uB2A5\uC131\uB3C4 \uC788\uC73C\uB098, \uC57D\uBB3C\uD22C\uC5EC\uB85C \uC778\uD55C \uCE58\uB8CC\uC801 \uC774\uB4DD\uC774 \uC704\uD5D8\uC744 \uC0C1\uD68C\uD560 \uAC00\uB2A5\uC131\uC774 \uC788\uB2E4.","sunbcontent":"Oseltamivir Phosphate|C|\uACBD\uAD6C\uC81C|#","drug_box":"10\uCEA1\uC290(10\uCEA1\uC290\/PTPx1)","stmt":"\uAE30\uBC00\uC6A9\uAE30, 25\u2103\uC774\uD558 \uBCF4\uAD00","drug_pic":"","pack_img":"","picto_img":"https:\/\/common.health.kr\/shared\/images\/pictogram\/black\/kor\/E03.jpg|https:\/\/common.health.kr\/shared\/images\/pictogram\/black\/kor\/F01.jpg","medititle":"\uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4\uC758 \uC99D\uC2DD\uC744 \uC5B5\uC81C\uD558\uC5EC \uB3C5\uAC10\uC744 \uCE58\uB8CC\uD558\uB294 \uC57D\uC785\uB2C8\uB2E4.","mediguide":"- \uC99D\uC0C1\uC774 \uAC1C\uC120\uB418\uC5B4\uB3C4 \uCC98\uBC29\uC77C \uB3D9\uC548 \uD22C\uC57D\uC744 \uC911\uB2E8\uD558\uC9C0 \uB9C8\uC138\uC694.brbr- \uAC00\uB2A5\uD55C \uD55C \uCD08\uAE30\uC5D0 \uC774 \uC57D\uC744 \uD22C\uC5EC\uD558\uC138\uC694.brbr- \uC18C\uC544\u00B7\uCCAD\uC18C\uB144\uC740 \uC774\uC0C1\uD589\uB3D9\uC758 \uC704\uD5D8\uC774 \uC788\uC744 \uC218 \uC788\uC73C\uBBC0\uB85C, \uC801\uC5B4\uB3C4 2\uC77C\uAC04 \uBCF4\uD638\uC790 \uB4F1\uC758 \uBCF4\uD638\uAD00\uCC30\uC774 \uD544\uC694\uD569\uB2C8\uB2E4.brbr- \uAD6C\uC5ED, \uAD6C\uD1A0\uAC00 \uB098\uD0C0\uB0A0 \uACBD\uC6B0 \uC74C\uC2DD\uACFC \uD568\uAED8 \uBCF5\uC6A9\uD558\uC138\uC694.brbr- \uC815\uD574\uC9C4 \uC6A9\uBC95, \uC6A9\uB7C9\uC744 \uC900\uC218\uD558\uC138\uC694.brbr- \uC774 \uC57D\uC740 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\uC811\uC885\uC744 \uB300\uC2E0\uD560 \uC218 \uC5C6\uC5B4\uC694.","effect":"1. \uC0DD\uD6C4 2\uC8FC \uC774\uC0C1 \uC2E0\uC0DD\uC544(\uC218\uD0DC \uD6C4 \uC5F0\uB839\uC774 36\uC8FC \uBBF8\uB9CC\uC778 \uC18C\uC544\uC5D0\uAC8C\uB294 \uC801\uC6A9\uB418\uC9C0 \uC54A\uB294\uB2E4)\uB97C \uD3EC\uD568\uD55C \uC18C\uC544 \uBC0F \uC131\uC778\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 A \uBC0F \uC778\uD50C\uB8E8\uC5D4\uC790 B \uBC14\uC774\uB7EC\uC2A4 \uAC10\uC5FC\uC99D(\uC778\uD50C\uB8E8\uC5D4\uC790 \uAC10\uC5FC\uC758 \uCD08\uAE30\uC99D\uC0C1 \uBC1C\uD604 48\uC2DC\uAC04 \uC774\uB0B4\uC5D0 \uD22C\uC5EC\uB97C \uC2DC\uC791\uD574\uC57C \uD55C\uB2E4.)brbr2. 1\uC138 \uC774\uC0C1\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 A \uBC0F \uC778\uD50C\uB8E8\uC5D4\uC790 B \uBC14\uC774\uB7EC\uC2A4 \uAC10\uC5FC\uC99D\uC758 \uC608\uBC29(\uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4 \uAC10\uC5FC\uC99D\uC5D0 \uB300\uD55C \uC608\uBC29\uC758 \uC77C\uCC28\uC694\uBC95\uC740 \uBC31\uC2E0\uC694\uBC95\uC774\uBBC0\uB85C \uBC31\uC2E0\uC5D0 \uB2F9\uD574 \uC720\uD589\uC8FC\uAC00 \uD3EC\uD568\uB418\uC5B4 \uC788\uC9C0 \uC54A\uC740 \uACBD\uC6B0 \uB610\uB294 \uBC31\uC2E0\uC758 \uD6A8\uACFC\uB97C \uAE30\uB300\uD560 \uC218 \uC5C6\uAC70\uB098 \uBC31\uC2E0 \uC811\uC885\uC744 \uD558\uC9C0 \uBABB\uD558\uB294 \uACBD\uC6B0\uC5D0 \uD55C\uD558\uC5EC \uC0AC\uC6A9\uD558\uBA70 \uC774 \uC57D\uC740 \uC608\uBC29\uC811\uC885\uC744 \uB300\uCCB4\uD560 \uC218 \uC5C6\uB2E4.)brbr","dosage":"1. \uC778\uD50C\uB8E8\uC5D4\uC790 A \uBC0F \uC778\uD50C\uB8E8\uC5D4\uC790 B \uBC14\uC774\uB7EC\uC2A4 \uAC10\uC5FC\uC99D : \uC778\uD50C\uB8E8\uC5D4\uC790 \uC99D\uC0C1\uC774 \uBC1C\uD604\uB41C \uCCAB\uC9F8 \uB610\uB294 \uB458\uC9F8 \uB0A0\uC5D0 \uCE58\uB8CC\uB97C \uC2DC\uC791\uD55C\uB2E4. \uC774 \uC57D\uC740 \uC74C\uC2DD\uBB3C \uC12D\uCDE8\uC640 \uAD00\uACC4\uC5C6\uC774 \uD22C\uC5EC\uD560 \uC218 \uC788\uC73C\uBA70 \uC77C\uBD80 \uD658\uC790\uC5D0\uC11C\uB294 \uC74C\uC2DD\uBB3C\uACFC \uD568\uAED8 \uBCF5\uC6A9 \uC2DC \uB0B4\uC57D\uC131\uC774 \uD638\uC804\uB420 \uC218 \uC788\uB2E4.brbr1) \uC131\uC778 \uBC0F 13\uC138 \uC774\uC0C1\uC758 \uCCAD\uC18C\uB144 :brbr\uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uB85C\uC11C 75 mg\uC744 1\uC77C 2\uD68C, 5\uC77C\uAC04 \uACBD\uAD6C\uD22C\uC5EC \uD55C\uB2E4. \uCEA1\uC290\uC744 \uC0BC\uD0A4\uAE30 \uC5B4\uB824\uC6B4 \uC131\uC778 \uBC0F 13\uC138 \uC774\uC0C1\uC758 \uCCAD\uC18C\uB144\uC740 \uC774 \uC57D \uD604\uD0C1\uC6A9 \uBD84\uB9D0\uC744 \uC774\uC6A9\uD558\uC5EC \uD22C\uC57D\uD55C\uB2E4.brbr2) 1\uC138 \uC774\uC0C1 12\uC138 \uC774\uD558\uC758 \uC18C\uC544 :brbr\uCEA1\uC290\uC744 \uC0BC\uD0AC \uC218 \uC788\uB294 \uCCB4\uC911\uC774 40 kg\uC744 \uCD08\uACFC\uD558\uB294 \uC18C\uC544 \uD658\uC790\uB294 \uC774 \uC57D \uD604\uD0C1\uC561 \uAD8C\uC7A5\uC6A9\uB7C9 \uB300\uC2E0 75mg \uCEA1\uC290\uC744 1\uC77C 2\uD68C \uB610\uB294 30mg \uCEA1\uC290\uACFC 45mg \uCEA1\uC290\uC744 1\uC77C 2\uD68C \uBCF5\uC6A9\uD560 \uC218 \uC788\uB2E4.brbr\uB2E4\uC74C \uC6A9\uB7C9\uD45C\uC5D0 \uB530\uB77C \uD22C\uC5EC\uD55C\uB2E4.brbr

\uCCB4\uC911<\/FONT><\/TD> 5\uC77C\uAC04\uC758 \uAD8C\uC7A5\uC6A9\uB7C9
(\uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uB85C\uC11C)<\/FONT><\/SPAN><\/TD> 		\uD604\uD0C1\uC561(6mg\/mL) \uC6A9\uB7C9<\/FONT><\/TD><\/TR>
\u2264 15 kg<\/FONT><\/TD> 30 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 5.0 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
15 kg<, \u2264 23 kg<\/FONT><\/SPAN><\/TD> 45 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 7.5 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
23 kg<, \u2264 40 kg<\/FONT><\/SPAN><\/TD> 60 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 10.0 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
> 40 kg<\/FONT><\/SPAN><\/TD> 75 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 12.5 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR><\/TABLE><\/P>brbr3) 2\uC8FC \uC774\uC0C1 1\uC138 \uBBF8\uB9CC \uC18C\uC544:brbr2\uC8FC\uC5D0\uC11C 12\uAC1C\uC6D4 \uC18C\uC544 \uD658\uC790\uC5D0 \uB300\uD55C \uAD8C\uC7A5 \uC6A9\uB7C9\uC740 \uC774 \uC57D\uC73C\uB85C\uC11C 3mg\/kg\uC744 1\uC77C 2\uD68C, 5\uC77C\uAC04 \uACBD\uAD6C\uD22C\uC5EC \uD55C\uB2E4. \uC218\uD0DC \uD6C4 \uC5F0\uB839\uC774 36\uC8FC \uBBF8\uB9CC\uC778 \uC18C\uC544\uC5D0\uAC8C\uB294 \uC801\uC6A9\uB418\uC9C0 \uC54A\uB294\uB2E4.brbr\uB2E4\uC74C \uC6A9\uB7C9\uD45C\uC5D0 \uB530\uB77C \uD22C\uC5EC\uD55C\uB2E4*.brbr

\uCCB4\uC911<\/FONT><\/TD> 5\uC77C\uAC04\uC758 \uAD8C\uC7A5\uC6A9\uB7C9
(\uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uB85C\uC11C)<\/FONT><\/SPAN><\/TD> 		\uD604\uD0C1\uC561(6mg\/mL) \uC6A9\uB7C9<\/FONT><\/TD><\/TR>
3 kg<\/FONT><\/SPAN><\/TD> 9 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 1.5 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
4 kg<\/FONT><\/SPAN><\/TD> 12 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 2.0 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
5 kg<\/FONT><\/SPAN><\/TD> 15 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 2.5 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
6 kg<\/FONT><\/SPAN><\/TD> 18 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 3.0 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
7 kg<\/FONT><\/SPAN><\/TD> 21 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 3.5 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
8 kg<\/FONT><\/SPAN><\/TD> 24 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 4.0 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
9 kg<\/FONT><\/SPAN><\/TD> 27 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 4.5 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
10 kg<\/FONT><\/SPAN><\/TD> 30 mg \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD> 5.0 mL \uC529 1\uC77C 2\uD68C<\/FONT><\/SPAN><\/TD><\/TR><\/TABLE><\/P>brbr* \uC774 \uD45C\uB294 \uC774 \uD658\uC790\uAD70\uC758 \uBAA8\uB4E0 \uAC00\uB2A5\uD55C \uCCB4\uC911\uC744 \uD3EC\uD568\uD558\uACE0 \uC788\uC9C0 \uC54A\uB2E4. 1\uC138 \uBBF8\uB9CC \uC18C\uC544\uB294 \uC774 \uC57D 3mg\/kg\uC744 \uBCF5\uC6A9\uD558\uB294 \uAC83\uC774 \uAD8C\uC7A5\uB41C\uB2E4.brbr\uD658\uC790\uC5D0\uAC8C \uD22C\uC5EC\uD558\uAE30 \uC804 \uC57D\uC0AC\uAC00 \uC774 \uC57D \uD604\uD0C1\uC561\uC744 \uC870\uC81C\uD558\uB294 \uAC83\uC774 \uAD8C\uC7A5\uB41C\uB2E4.brbrbrbr4) \uC2E0\uAE30\uB2A5\uC7A5\uC560 \uD658\uC790brbr\uD06C\uB808\uC544\uD2F0\uB2CC \uCCAD\uC18C\uC728\uC774 60 mL\/min \uC774\uC0C1\uC778 \uD658\uC790\uB294 \uC6A9\uB7C9\uC870\uC808\uC774 \uD544\uC694\uD558\uC9C0 \uC54A\uC73C\uBA70, 30 ~ 60 mL\/min\uC778 \uD658\uC790\uB294 1\uC77C 2\uD68C 30 mg\uC73C\uB85C \uAC10\uB7C9\uD558\uC5EC 5\uC77C\uAC04 \uD22C\uC5EC\uAC00 \uAD8C\uC7A5\uB41C\uB2E4. \uD06C\uB808\uC544\uD2F0\uB2CC \uCCAD\uC18C\uC728\uC774 10 ~ 30 mL\/min\uC778 \uD658\uC790\uB294 1\uC77C 1\uD68C 30 mg\uC73C\uB85C \uAC10\uB7C9\uD558\uC5EC 5\uC77C\uAC04 \uD22C\uC5EC\uAC00 \uAD8C\uC7A5\uB41C\uB2E4. \uC8FC\uAE30\uC801\uC73C\uB85C \uD608\uC561\uD22C\uC11D\uC744 \uBC1B\uB294 \uD658\uC790\uB294 \uCE58\uB8CC \uBC94\uC704\uC758 \uD608\uC911 \uB18D\uB3C4\uB97C \uC720\uC9C0\uD558\uAE30 \uC704\uD574 \uB9E4 \uD22C\uC11D \uD6C4 \uC774 \uC57D 30mg \uC6A9\uB7C9\uC744 \uD22C\uC5EC\uD574\uC57C \uD558\uBA70 \uD22C\uC5EC\uAE30\uAC04\uC740 5\uC77C\uC744 \uCD08\uACFC\uD574\uC11C\uB294 \uC548\uB41C\uB2E4. \uB9CC\uC57D \uC778\uD50C\uB8E8\uC5D4\uC790 \uC99D\uC0C1\uC774 \uD22C\uC11D \uAE30\uAC04 \uC0AC\uC774 48\uC2DC\uAC04 \uB3D9\uC548\uC5D0 \uBC1C\uC0DD\uD55C\uB2E4\uBA74 \uD22C\uC11D \uC2DC\uC791 \uC804 \uD22C\uC5EC\uD560 \uC218\uB3C4 \uC788\uB2E4. \uBCF5\uB9C9\uD22C\uC11D\uC758 \uACBD\uC6B0 \uD22C\uC11D \uD6C4 \uC774 \uC57D 30mg\uB97C \uB2E8\uD68C \uD22C\uC5EC\uD558\uB294 \uAC83\uC774 \uAD8C\uC7A5\uB41C\uB2E4. \uD22C\uC11D\uC744 \uBC1B\uC9C0 \uC54A\uB294 \uC2E0\uBD80\uC804\uB9D0\uAE30 \uD658\uC790 (\uC608. \uD06C\uB808\uC544\uD2F0\uB2CC \uCCAD\uC18C\uC728 10mL\/min \uBBF8\uB9CC)\uC5D0 \uB300\uD55C \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC758 \uC57D\uB3D9\uD559\uC740 \uC5F0\uAD6C\uB418\uC9C0 \uC54A\uC558\uC73C\uBBC0\uB85C \uC774 \uD658\uC790\uB4E4\uC5D0 \uB300\uD55C \uAD8C\uC7A5 \uC6A9\uB7C9\uC740 \uC81C\uACF5\uB418\uC9C0 \uC54A\uB294\uB2E4.brbr5) \uAC04\uAE30\uB2A5\uC7A5\uC560 \uD658\uC790brbr\uACBD\uC99D\uC5D0\uC11C \uC911\uB4F1\uB3C4 \uAC04\uC7A5\uC560(Child-Pugh score \u2264 9) \uC131\uC778 \uD658\uC790\uC5D0 \uB300\uD55C \uCE58\uB8CC \uC2DC \uC6A9\uB7C9\uC870\uC808\uC740 \uD544\uC694\uD558\uC9C0 \uC54A\uB2E4.brbrbrbr2. \uC778\uD50C\uB8E8\uC5D4\uC790 A \uBC0F \uC778\uD50C\uB8E8\uC5D4\uC790 B \uBC14\uC774\uB7EC\uC2A4 \uAC10\uC5FC\uC99D\uC758 \uC608\uBC29brbr1) \uC131\uC778 \uBC0F 13\uC138 \uC774\uC0C1\uC758 \uCCAD\uC18C\uB144 :brbr\uAC10\uC5FC\uB41C \uC0AC\uB78C\uACFC \uAC00\uAE4C\uC6B4 \uC811\uCD09\uAD00\uACC4\uC5D0 \uC788\uB294 \uACBD\uC6B0, \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uB85C\uC11C 75 mg\uC744 1\uC77C 1\uD68C, 10\uC77C\uAC04 \uACBD\uAD6C\uD22C\uC5EC\uD55C\uB2E4. \uAC10\uC5FC\uB41C \uC0AC\uB78C\uACFC \uC811\uCD09\uD55C\uC9C0 2\uC77C\uB0B4\uC5D0 \uD22C\uC5EC\uB97C \uC2DC\uC791\uD55C\uB2E4.brbr\uC778\uD50C\uB8E8\uC5D4\uC790\uAC00 \uC720\uD589\uD558\uB294 \uB3D9\uC548 \uC608\uBC29\uC744 \uC704\uD55C \uAD8C\uC7A5\uC6A9\uB7C9\uC740 75 mg\uC744 1\uC77C 1\uD68C \uD22C\uC5EC\uD558\uB294 \uAC83\uC774\uB2E4. \uC774 \uC57D\uC758 \uC548\uC804\uC131 \uBC0F \uC720\uD6A8\uC131\uC740 6\uC8FC\uAE4C\uC9C0 \uC99D\uBA85\uB418\uC5B4 \uC788\uB2E4. \uC774 \uC57D\uBB3C\uC744 \uBCF5\uC6A9\uD558\uB294 \uB3D9\uC548 \uC608\uBC29\uD6A8\uACFC\uAC00 \uC9C0\uC18D\uB41C\uB2E4.brbr2) 1\uC138 \uC774\uC0C1 12\uC138 \uC774\uD558\uC758 \uC18C\uC544 :brbr\uCEA1\uC290\uC744 \uC0BC\uD0AC \uC218 \uC788\uB294 \uCCB4\uC911\uC774 40 kg\uC744 \uCD08\uACFC\uD558\uB294 \uC18C\uC544 \uD658\uC790\uB294 \uC774 \uC57D \uD604\uD0C1\uC561 \uAD8C\uC7A5\uC6A9\uB7C9 \uB300\uC2E0 75mg \uCEA1\uC290\uC744 1\uC77C 1\uD68C \uB610\uB294 30mg \uCEA1\uC290\uACFC 45mg \uCEA1\uC290\uC744 1\uC77C 1\uD68C, 10\uC77C\uAC04 \uBCF5\uC6A9\uD560 \uC218 \uC788\uB2E4.brbr\uB2E4\uC74C \uC6A9\uB7C9\uD45C\uC5D0 \uB530\uB77C \uD22C\uC5EC\uD55C\uB2E4.brbr

\uCCB4\uC911<\/FONT><\/TD> 10\uC77C\uAC04\uC758 \uAD8C\uC7A5\uC6A9\uB7C9
(\uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uB85C\uC11C)<\/FONT><\/SPAN><\/TD> 		\uD604\uD0C1\uC561(6mg\/mL) \uC6A9\uB7C9<\/FONT><\/TD><\/TR>
\u2264 15 kg<\/FONT><\/TD> 30 mg \uC529 1\uC77C 1\uD68C<\/FONT><\/SPAN><\/TD> 5.0 mL \uC529 1\uC77C 1\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
15 kg<, \u2264 23 kg<\/FONT><\/SPAN><\/TD> 45 mg \uC529 1\uC77C 1\uD68C<\/FONT><\/SPAN><\/TD> 7.5 mL \uC529 1\uC77C 1\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
23 kg<, \u2264 40 kg<\/FONT><\/SPAN><\/TD> 60 mg \uC529 1\uC77C 1\uD68C<\/FONT><\/SPAN><\/TD> 10.0 mL \uC529 1\uC77C 1\uD68C<\/FONT><\/SPAN><\/TD><\/TR>
> 40 kg<\/FONT><\/SPAN><\/TD> 75 mg \uC529 1\uC77C 1\uD68C<\/FONT><\/SPAN><\/TD> 12.5 mL \uC529 1\uC77C 1\uD68C<\/FONT><\/SPAN><\/TD><\/TR><\/TABLE><\/P>brbr\uD658\uC790\uC5D0\uAC8C \uD22C\uC5EC\uD558\uAE30 \uC804 \uC57D\uC0AC\uAC00 \uC774 \uC57D \uD604\uD0C1\uC561\uC744 \uC870\uC81C\uD558\uB294 \uAC83\uC774 \uAD8C\uC7A5\uB41C\uB2E4.brbr\u203B 1\uC138 \uBBF8\uB9CC \uC18C\uC544\uC5D0 \uB300\uD55C \uC778\uD50C\uB8E8\uC5D4\uC790 A \uBC0F B \uBC14\uC774\uB7EC\uC2A4 \uAC10\uC5FC\uC99D \uC608\uBC29\uC758 \uC548\uC804\uC131 \uBC0F \uC720\uD6A8\uC131\uC740 \uD3C9\uAC00\uB418\uC9C0 \uC54A\uC558\uB2E4.brbrbrbr3) \uC2E0\uAE30\uB2A5\uC7A5\uC560 \uD658\uC790brbr\uD06C\uB808\uC544\uD2F0\uB2CC\uCCAD\uC18C\uC728\uC774 60 mL\/min \uC774\uC0C1\uC778 \uD658\uC790\uB294 \uC6A9\uB7C9\uC870\uC808\uC774 \uD544\uC694\uD558\uC9C0 \uC54A\uC73C\uBA70, 30 \uFF5E 60 mL\/min\uC778 \uD658\uC790\uB294 1\uC77C 1\uD68C 30 mg\uC73C\uB85C \uAC10\uB7C9\uD558\uC5EC \uD22C\uC5EC\uAC00 \uAD8C\uC7A5\uB41C\uB2E4. \uD06C\uB808\uC544\uD2F0\uB2CC \uCCAD\uC18C\uC728\uC774 10 \uFF5E 30 mL\/min\uC778 \uD658\uC790\uB294 1\uC77C 1\uD68C 30 mg\uC73C\uB85C \uAC10\uB7C9\uD558\uC5EC \uACA9\uC77C \uD22C\uC5EC\uAC00 \uAD8C\uC7A5\uB41C\uB2E4. \uC8FC\uAE30\uC801\uC73C\uB85C \uD608\uC561\uD22C\uC11D\uC744 \uBC1B\uB294 \uD658\uC790\uB294 \uCE58\uB8CC \uBC94\uC704\uC758 \uD608\uC911 \uB18D\uB3C4\uB97C \uC720\uC9C0\uD558\uAE30 \uC704\uD574 \uB9E4 2\uBC88\uC758 \uD22C\uC11D \uD6C4 \uC774 \uC57D 30mg \uC6A9\uB7C9\uC744 \uD22C\uC5EC\uD574\uC57C \uD55C\uB2E4. \uCD08\uD68C \uC6A9\uB7C9\uC740 \uD22C\uC11D \uC2DC\uC791\uC804 \uD22C\uC5EC\uD560 \uC218\uB3C4 \uC788\uB2E4. \uBCF5\uB9C9\uD22C\uC11D\uC758 \uACBD\uC6B0 \uC8FC 1\uD68C \uD22C\uC11D \uD6C4 \uC774 \uC57D 30mg\uB97C \uD22C\uC5EC\uD558\uB294 \uAC83\uC774 \uAD8C\uC7A5\uB41C\uB2E4. \uD22C\uC11D\uC744 \uBC1B\uC9C0 \uC54A\uB294 \uC2E0\uBD80\uC804\uB9D0\uAE30 \uD658\uC790 (\uC608. \uD06C\uB808\uC544\uD2F0\uB2CC \uCCAD\uC18C\uC728 10mL\/min\uBBF8\uB9CC)\uC5D0 \uB300\uD55C \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC758 \uC57D\uB3D9\uD559\uC740 \uC5F0\uAD6C\uB418\uC9C0 \uC54A\uC558\uC73C\uBBC0\uB85C \uC774 \uD658\uC790\uB4E4\uC5D0 \uB300\uD55C \uAD8C\uC7A5 \uC6A9\uB7C9\uC740 \uC81C\uACF5\uB418\uC9C0 \uC54A\uB294\uB2E4.brbr4) \uAC04\uAE30\uB2A5\uC7A5\uC560 \uD658\uC790brbr\uACBD\uC99D\uC5D0\uC11C \uC911\uB4F1\uB3C4 \uAC04\uC7A5\uC560(Child-Pugh score \u2264 9) \uC131\uC778 \uD658\uC790\uC5D0 \uB300\uD55C \uC608\uBC29\uC2DC \uC6A9\uB7C9\uC870\uC808\uC740 \uD544\uC694\uD558\uC9C0 \uC54A\uB2E4.","caution":"1. \uACBD\uACE0\r\n

<\/P>1) \uC774 \uC57D\uC740 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\uC811\uC885\uC744 \uB300\uC2E0\uD560 \uC218 \uC5C6\uB2E4. \uC774 \uC57D\uC758 \uC0AC\uC6A9\uACFC \uB9E4\uB144\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\uC811\uC885 \uAC04\uC5D0\uB294 \uC5B4\uB5A4 \uC0C1\uAD00\uAD00\uACC4\uB3C4 \uC5C6\uB2E4. \uC778\uD50C\uB8E8\uC5D4\uC790\uC5D0 \uB300\uD55C \uC608\uBC29\uD6A8\uACFC\uB294 \uC774 \uC57D\uC744 \uC0AC\uC6A9\uD558\uB294 \uB3D9\uC548\uC5D0\uB9CC \uC9C0\uC18D\uB41C\uB2E4. \uD604\uC7AC \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4\uAC00 \uD574\uB2F9 \uC9C0\uC5ED\uC5D0 \uC720\uD589\uD568\uC744 \uB098\uD0C0\uB0B4\uB294 \uC2E0\uB8B0\uD560 \uB9CC\uD55C \uC5ED\uD559 \uC790\uB8CC\uAC00 \uC788\uC744 \uACBD\uC6B0\uC5D0 \uC774 \uC57D\uC744 \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uBC0F \uC608\uBC29\uC5D0 \uC0AC\uC6A9\uD55C\uB2E4.\r\n

<\/P>2) \uC778\uD50C\uB8E8\uC5D4\uC790 A, B \uC774\uC678\uC758 \uAC10\uC5FC \uCE58\uB8CC\uC5D0 \uB300\uD55C \uC774 \uC57D\uC758 \uC548\uC804\uC131 \uBC0F \uC720\uD6A8\uC131\uC740 \uC5F0\uAD6C\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>3) \uC774 \uC57D\uC744 \uBCF5\uC6A9\uC911\uC778 \uC778\uD50C\uB8E8\uC5D4\uC790 \uD658\uC790\uB4E4 \uC911 \uC8FC\uB85C \uC18C\uC544\u2219\uCCAD\uC18C\uB144 \uD658\uC790\uC5D0\uC11C \uACBD\uB828\uACFC \uC12C\uB9DD\uACFC \uAC19\uC740 \uC2E0\uACBD\uC815\uC2E0\uACC4 \uC774\uC0C1\uBC18\uC751\uC774 \uBCF4\uACE0\uB418\uC5C8\uB2E4. \uB4DC\uBB3C\uAC8C \uC774\uB7EC\uD55C \uC774\uC0C1\uBC18\uC751\uC740 \uC0AC\uACE0\uB85C \uC774\uC5B4\uC84C\uB2E4. \uC774\uB7EC\uD55C \uC774\uC0C1\uBC18\uC751\uC774 \uC774 \uC57D \uD22C\uC5EC\uB85C \uC778\uD55C \uAC83\uC778\uC9C0\uB294 \uC54C\uB824\uC838 \uC788\uC9C0 \uC54A\uACE0, \uC774 \uC57D\uC744 \uBCF5\uC6A9\uD558\uC9C0 \uC54A\uC558\uB358 \uD658\uC790\uC5D0\uC11C\uB3C4 \uC774\uB7EC\uD55C \uC815\uC2E0\uC2E0\uACBD\uACC4 \uC774\uC0C1\uBC18\uC751\uC774 \uBCF4\uACE0\uB418\uC5C8\uB2E4.\r\n

<\/P>\uD2B9\uD788 \uC18C\uC544\uC640 \uCCAD\uC18C\uB144 \uD658\uC790\uC758 \uC774\uC0C1\uD589\uB3D9 \uBC1C\uD604\uC5D0 \uB300\uD558\uC5EC \uBA74\uBC00\uD788 \uBAA8\uB2C8\uD130\uB9C1 \uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>10\uC138 \uC774\uC0C1\uC758 \uC18C\uC544 \uD658\uC790\uC5D0 \uC788\uC5B4\uC11C\uB294 \uC778\uACFC\uAD00\uACC4\uB294 \uBD88\uBD84\uBA85\uD558\uC9C0\uB9CC \uC774 \uC57D\uC758 \uBCF5\uC6A9 \uD6C4\uC5D0 \uC774\uC0C1\uD589\uB3D9\uC774 \uBC1C\uD604\uD558\uACE0 \uCD94\uB77D \uB4F1\uC758 \uC0AC\uACE0\uC5D0 \uC774\uB978 \uC608\uAC00 \uC8FC\uB85C \uC77C\uBCF8\uC5D0\uC11C \uBCF4\uACE0\uB418\uC5B4 \uC788\uB2E4. \uC774 \uB54C\uBB38\uC5D0 \uC774 \uC5F0\uB839\uB300\uC758 \uD658\uC790\uC5D0\uAC8C\uB294 \uD569\uBCD1\uC99D\uC774\uB098 \uACFC\uAC70\uBCD1\uB825 \uB4F1\uC73C\uB85C\uBD80\uD130 \uACE0\uC704\uD5D8\uD658\uC790\uB85C \uD310\uB2E8\uB418\uB294 \uACBD\uC6B0\uB97C \uC81C\uC678\uD558\uACE0\uB294 \uC6D0\uCE59\uC801\uC73C\uB85C \uC774 \uC57D \uC0AC\uC6A9\uC744 \uD558\uC9C0 \uC54A\uB294\uB2E4.\r\n

<\/P>\uC18C\uC544, \uCCAD\uC18C\uB144\uC5D0 \uC788\uC5B4 \uB9CC\uC77C\uC758 \uC0AC\uACE0\uB97C \uBC29\uC9C0\uD558\uAE30 \uC704\uD558\uC5EC \uC774 \uC57D\uC5D0 \uC758\uD55C \uCE58\uB8CC\uAC00 \uAC1C\uC2DC\uB41C \uC774\uD6C4\uC5D0 \uC774\uC0C1\uD589\uB3D9\uC758 \uBC1C\uD604 \uC704\uD5D8\uC774 \uC788\uB2E4\uB294 \uAC83\uACFC \uC790\uD0DD\uC5D0\uC11C \uC694\uC591\uD558\uB294 \uACBD\uC6B0 \uC801\uC5B4\uB3C4 2\uC77C\uAC04 \uBCF4\uD638\uC790 \uB4F1\uC740 \uC18C\uC544, \uCCAD\uC18C\uB144\uC774 \uD63C\uC790 \uC788\uC9C0 \uC54A\uB3C4\uB85D \uBC30\uB824\uD560 \uAC83\uC5D0 \uB300\uD574 \uD658\uC790 \uBC0F \uAC00\uC871\uC5D0\uAC8C \uC124\uBA85\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>\uB610\uD55C \uC778\uD50C\uB8E8\uC5D4\uC790 \uB1CC\uC99D \uB4F1\uC5D0 \uC758\uD574\uC11C\uB3C4 \uB3D9\uC77C\uD55C \uC99D\uC0C1\uC774 \uB098\uD0C0\uB09C\uB2E4\uB294 \uBCF4\uACE0\uAC00 \uC788\uC73C\uBBC0\uB85C \uC704\uC640 \uB3D9\uC77C\uD558\uAC8C \uC124\uBA85\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>2. \uB2E4\uC74C \uD658\uC790\uC5D0\uB294 \uD22C\uC5EC\uD558\uC9C0 \uB9D0 \uAC83.\r\n

<\/P>\uC774 \uC57D \uB610\uB294 \uC774 \uC57D\uC758 \uAD6C\uC131\uC131\uBD84\uC5D0 \uB300\uD55C \uACFC\uBBFC\uBC18\uC751 \uD658\uC790\r\n

<\/P>3. \uB2E4\uC74C \uD658\uC790\uC5D0\uB294 \uC2E0\uC911\uD788 \uD22C\uC5EC\uD560 \uAC83.\r\n

<\/P>1) \uC2E0\uBD80\uC804 \uD658\uC790\r\n

<\/P>\uC911\uB4F1\uC99D(\uD06C\uB808\uC544\uD2F0\uB2CC\uCCAD\uC18C\uC728 30 \uFF5E 60 mL\/min\uC778 \uD658\uC790) \uBC0F \uC911\uC99D(\uD06C\uB808\uC544\uD2F0\uB2CC\uCCAD\uC18C\uC728 10 \uFF5E 30 mL\/min\uC778 \uD658\uC790)\uC758 \uC2E0\uBD80\uC804 \uD658\uC790, \uD608\uC561\uD22C\uC11D \uB610\uB294 \uBCF5\uB9C9\uD22C\uC11D \uD658\uC790\uC5D0\uAC8C \uC774 \uC57D\uC744 \uD22C\uC5EC \uC2DC \uC6A9\uB7C9\uC870\uC808\uC774 \uD544\uC694\uD558\uB2E4(\uC6A9\uBC95\uC6A9\uB7C9\uD56D \uCC38\uC870). \uC774 \uC57D\uC740 \uD22C\uC11D\uC744 \uBC1B\uC9C0 \uC54A\uB294 \uB9D0\uAE30 \uC2E0\uBD80\uC804 \uD658\uC790(\uC608, \uD06C\uB808\uC544\uD2F0\uB2CC\uCCAD\uC18C\uC728 10ml\/min \uBBF8\uB9CC) \uC5D0\uAC8C\uB294 \uAD8C\uC7A5\uB418\uC9C0 \uC54A\uB294\uB2E4. \uC2E0\uBD80\uC804 \uC18C\uC544 \uD658\uC790\uC5D0\uB294 \uC774 \uC57D\uC758 \uC548\uC804\uC131 \uBC0F \uC720\uD6A8\uC131\uC5D0 \uB300\uD55C \uC790\uB8CC\uAC00 \uC5C6\uB2E4.\r\n

<\/P>2) \uACE0\uC704\uD5D8\uAD70 \uD658\uC790(\uCC9C\uC2DD, \uB9CC\uC131 \uAE30\uAD00\uC9C0\uC5FC, \uBA74\uC5ED\uC5B5\uC81C)(\uC0AC\uC6A9 \uACBD\uD5D8\uC774 \uB9E4\uC6B0 \uB4DC\uBB3C\uB2E4.)\r\n

<\/P>4. \uC774\uC0C1\uBC18\uC751\r\n

<\/P>\uC778\uD50C\uB8E8\uC5D4\uC790\uC5D0 \uAC10\uC5FC\uB41C 2,647\uBA85 \uC774\uC0C1\uC758 \uC131\uC778\/\uCCAD\uC18C\uB144 \uBC0F 858\uBA85 \uC774\uC0C1\uC758 \uC18C\uC544 \uD658\uC790\uC640 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29 \uBAA9\uC801\uC73C\uB85C \uC774 \uC57D\uC744 \uD22C\uC5EC\uD55C 1,945\uBA85 \uC774\uC0C1\uC758 \uC131\uC778\/\uCCAD\uC18C\uB144 \uBC0F 148\uBA85 \uC774\uC0C1\uC758 \uC18C\uC544\uC5D0\uC11C\uC758 \uC784\uC0C1\uC2DC\uD5D8 \uACB0\uACFC\uB97C \uBC14\uD0D5\uC73C\uB85C \uC774 \uC57D\uC758 \uC804\uCCB4\uC801\uC778 \uC548\uC804\uC131\uC744 \uD3C9\uAC00\uD558\uC600\uB2E4. \uC131\uC778\/\uCCAD\uC18C\uB144\uC5D0 \uB300\uD55C \uCE58\uB8CC\uC5F0\uAD6C \uC911 \uAC00\uC7A5 \uBE48\uBC88\uD558\uAC8C \uBCF4\uACE0\uB41C \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\uC740 \uAD6C\uC5ED, \uAD6C\uD1A0 \uBC0F \uB450\uD1B5\uC774\uC5C8\uB2E4. \uC774 \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\uC740 \uB300\uBD80\uBD84 \uC77C\uD68C\uC131\uC774\uC5C8\uACE0 \uD22C\uC5EC \uCCAB\uB0A0 \uB610\uB294 \uC774\uD2C0\uC9F8\uC5D0 \uBC1C\uC0DD\uD558\uC5EC \uC774\uD6C4 1 \uFF5E 2\uC77C\uB0B4\uC5D0 \uD574\uC18C\uB418\uC5C8\uB2E4. \uC131\uC778\/\uCCAD\uC18C\uB144\uC5D0 \uB300\uD55C \uC608\uBC29\uC5F0\uAD6C \uC911 \uAC00\uC7A5 \uBE48\uBC88\uD558\uAC8C \uBCF4\uACE0\uB41C \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\uC740 \uAD6C\uC5ED, \uAD6C\uD1A0, \uB450\uD1B5 \uBC0F \uD1B5\uC99D\uC774\uC5C8\uB2E4. \uC18C\uC544\uC5D0\uC11C \uAC00\uC7A5 \uBE48\uBC88\uD558\uAC8C \uBCF4\uACE0\uB41C \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\uC740 \uAD6C\uD1A0\uC600\uB2E4. \uB300\uBD80\uBD84 \uD658\uC790\uC5D0\uC11C \uC774\uB7F0 \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\uC740 \uC57D \uBCF5\uC6A9\uC744 \uC911\uB2E8\uD560 \uC815\uB3C4\uC5D0 \uC774\uB974\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>1) \uC131\uC778\/\uCCAD\uC18C\uB144\uC5D0\uC11C\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uBC0F \uC608\uBC29 : \uC131\uC778\/\uCCAD\uC18C\uB144\uC5D0\uC11C\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uBC0F \uC608\uBC29 \uC5F0\uAD6C\uC758 \uAD8C\uC7A5\uC6A9\uB7C9(\uCE58\uB8CC : 75 mg\uC529 1\uC77C 2\uD68C 5\uC77C\uAC04 \uD22C\uC5EC, \uC608\uBC29 : 75 mg \uC529 1\uC77C 1\uD68C 6\uC8FC\uAE4C\uC9C0 \uD22C\uC5EC)\uC5D0\uC11C \uAC00\uC7A5 \uBE48\uBC88\uD558\uAC8C \uBC1C\uC0DD\uD558\uC600\uACE0(1 % \uC774\uC0C1), \uC704\uC57D\uD22C\uC5EC\uAD70\uBCF4\uB2E4 \uBC1C\uC0DD\uB960\uC774 1 %\uC774\uC0C1 \uB192\uC558\uB358 \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\uC740 \uAD6C\uC5ED, \uAD6C\uD1A0, \uB450\uD1B5 \uBC0F \uD1B5\uC99D\uC774\uC5C8\uB2E4(\uD45C1 \uCC38\uACE0). \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uC5F0\uAD6C\uB294 \uAC74\uAC15\uD55C \uC131\uC778\/\uCCAD\uC18C\uB144 \uBC0F \uACE0\uC704\uD5D8\uAD70 \uD658\uC790(\uC778\uD50C\uB8E8\uC5D4\uC790 \uD569\uBCD1\uC99D\uC758 \uC704\uD5D8\uC774 \uC788\uB294 \uD658\uC790. \uC989, \uACE0\uB839\uC790 \uBC0F \uB9CC\uC131 \uC2EC\uC7A5\uC9C8\uD658 \uB610\uB294 \uD638\uD761\uAE30 \uC9C8\uD658\uC774 \uC788\uB294 \uD658\uC790)\uB97C \uB300\uC0C1\uC73C\uB85C \uD558\uC600\uB2E4. \uC77C\uBC18\uC801\uC73C\uB85C \uACE0\uC704\uD5D8\uAD70 \uD658\uC790\uC5D0\uC11C\uC758 \uC548\uC804\uC131 \uC591\uC0C1\uC740 \uAC74\uAC15\uD55C \uC131\uC778\/\uCCAD\uC18C\uB144\uACFC \uC9C8\uC801\uC778 \uBA74\uC5D0\uC11C \uC720\uC0AC\uD558\uC600\uB2E4. \uB354 \uC624\uB798 \uC57D\uBB3C\uC744 \uBCF5\uC6A9\uD588\uC74C\uC5D0\uB3C4 \uBD88\uAD6C\uD558\uACE0 \uC608\uBC29 \uC5F0\uAD6C(75 mg\uC529 1\uC77C 1\uD68C 6\uC8FC\uAE4C\uC9C0 \uD22C\uC5EC)\uC5D0\uC11C \uBCF4\uACE0\uB41C \uC548\uC804\uC131 \uC591\uC0C1\uC740 \uCE58\uB8CC \uC5F0\uAD6C\uC5D0\uC11C \uAD00\uCC30\uB41C \uAC83(\uD45C1)\uACFC \uC9C8\uC801\uC778 \uBA74\uC5D0\uC11C \uC720\uC0AC\uD558\uC600\uB2E4.\r\n

<\/P>2) \uC774 \uC57D\uC744 \uBCF5\uC6A9\uD55C \uD658\uC790\uC5D0\uC11C \uBC1C\uC0DD\uD55C 1 %\uBBF8\uB9CC\uC758 \uC774\uC0C1\uBC18\uC751\uC5D0\uB294 \uBD88\uC548\uC815\uD615 \uD611\uC2EC\uC99D, \uBE48\uD608, \uC704\uB9C9\uC131 \uB300\uC7A5\uC5FC, \uD3D0\uB834, \uD3B8\uB3C4\uC8FC\uC704\uB18D\uC591, \uC0C1\uC644\uACE8 \uACE8\uC808, \uD658\uAC01, \uACBD\uB828, \uD53C\uBD80\uC5FC, \uBC1C\uC9C4, \uB450\uB4DC\uB7EC\uAE30, \uC2B5\uC9C4 \uB4F1\uC774 \uC788\uC5C8\uB2E4.\r\n

<\/P>3) \uACE0\uB839\uC790\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uBC0F \uC608\uBC29 : \uC774 \uC57D\uC774\uB098 \uC704\uC57D\uC744 \uD22C\uC5EC\uD55C 942\uBA85\uC758 \uACE0\uB839\uC790\uC5D0\uC11C\uC758 \uC548\uC804\uC131 \uC591\uC0C1\uC744 \uC80A\uC740 \uC0AC\uB78C(65\uC138 \uC774\uD558)\uACFC \uBE44\uAD50\uD588\uC744 \uB54C \uC784\uC0C1\uC801\uC73C\uB85C \uC758\uBBF8 \uC788\uB294 \uCC28\uC774\uAC00 \uC5C6\uC5C8\uB2E4.\r\n

<\/P>\r\n[&C1]* \uC774 \uC57D \uD22C\uC5EC \uC2DC \uC704\uC57D\uBCF4\uB2E4 1 % \uC774\uC0C1 \uBE48\uBC88\uD558\uAC8C \uBC1C\uC0DD\uD55C \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\r\n

<\/P>\uC774 \uC57D \uD22C\uC5EC \uAD70\uC5D0\uC11C\uC758 \uC774\uC0C1\uBC18\uC751 \uBC1C\uC0DD\uBE48\uB3C4\uB97C \uC704 \uD45C\uC5D0 \uC81C\uC2DC\uD558\uC600\uC73C\uBA70, \uBE48\uB3C4\uB294 \uB9E4\uC6B0 \uC790\uC8FC(\u22651\/10), \uC790\uC8FC(\u22651\/100, <1\/10)\uB85C \uC815\uC758\uD55C\uB2E4.\r\n

<\/P>4) \uC784\uC0C1\uC801\uC73C\uB85C \uC720\uC758\uD55C \uC774\uC0C1\uBC18\uC751\r\n

<\/P>\uBC1C\uC0DD\uBE48\uB3C4\uB294 \uBA85\uD655\uD558\uC9C0 \uC54A\uC73C\uB098, \uC774 \uC57D\uC758 \uD22C\uC5EC\uB85C \uCD94\uAC00\uC801\uC73C\uB85C \uB098\uD0C0\uB0A0 \uC218 \uC788\uB294 \uC774\uC0C1\uBC18\uC751\uC740 \uB2E4\uC74C\uACFC \uAC19\uB2E4.\r\n

<\/P>(1) \uC1FC\uD06C, \uC544\uB098\uD544\uB77D\uC2DC\uC2A4\uBC18\uC751 : \uC1FC\uD06C\uC640 \uC544\uB098\uD544\uB77D\uC2DC\uC2A4\uBC18\uC751\uC774 \uBC1C\uC0DD\uD560 \uC218 \uC788\uC73C\uBA70, \uD658\uC790\uB97C \uC2E0\uC911\uD788 \uAD00\uCC30\uD574\uC57C \uD558\uBA70, \uB9CC\uC77C \uB450\uB4DC\uB7EC\uAE30, \uC548\uBA74 \uBC0F \uD6C4\uB450 \uBD80\uC885, \uD638\uD761\uACE4\uB780, \uD608\uC555\uC800\uD558\uC640 \uAC19\uC740 \uC99D\uC0C1\uC774 \uB098\uD0C0\uB098\uBA74 \uD22C\uC5EC\uB97C \uC911\uB2E8\uD558\uACE0, \uC801\uC808\uD55C \uC870\uCE58\uB97C \uCDE8\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>(2) \uD3D0\uB834 : \uD3D0\uB834\uC774 \uBC1C\uC0DD\uD558\uB294 \uAC83\uC73C\uB85C \uBCF4\uACE0\uB418\uC5C8\uB2E4. \uB9CC\uC77C \uC774\uC0C1\uC774 \uAD00\uCC30\uB418\uBA74, \uBC29\uC0AC\uC120\uAC80\uC0AC\uC640 \uC801\uC808\uD55C \uBC29\uBC95\uC744 \uD1B5\uD574 \uC6D0\uC778(\uC608, \uC57D\uBB3C, \uAC10\uC5FC)\uC744 \uACB0\uC815\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>(3) \uAC04\uC5FC, \uAC04\uAE30\uB2A5 \uC774\uC0C1, \uD669\uB2EC : AST, ALT, \u03B3-GTP \uBC0F ALP\uC758 \uD604\uC800\uD55C \uC99D\uAC00\uB97C \uC218\uBC18\uD558\uB294 \uAC04\uC5FC, \uAC04\uAE30\uB2A5 \uC774\uC0C1, \uD669\uB2EC\uC774 \uBC1C\uC0DD\uD560 \uC218 \uC788\uB2E4. \uD658\uC790\uB4E4\uC744 \uC2E0\uC911\uD788 \uAD00\uCC30\uD558\uACE0, \uB9CC\uC77C \uC774\uC0C1\uC774 \uBC1C\uC0DD\uD558\uBA74 \uD22C\uC5EC\uB97C \uC911\uB2E8\uD558\uACE0 \uC801\uC808\uD55C \uC870\uCE58\uB97C \uCDE8\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>(4) \uD53C\uBD80\uC810\uB9C9\uC548\uC99D\uD6C4\uAD70(\uC2A4\uD2F0\uBE10\uC2A4-\uC874\uC2A8 \uC99D\uD6C4\uAD70), \uB3C5\uC131\uD45C\uD53C\uAD34\uC0AC\uC6A9\uD574(\uB9AC\uC5D8\uC99D\uD6C4\uAD70) : \uD53C\uBD80\uC810\uB9C9\uC548\uC99D\uD6C4\uAD70(\uC2A4\uD2F0\uBE10\uC2A4-\uC874\uC2A8 \uC99D\uD6C4\uAD70), \uB3C5\uC131\uD45C\uD53C\uAD34\uC0AC\uC6A9\uD574(\uB9AC\uC5D8\uC99D\uD6C4\uAD70) \uB4F1\uACFC \uAC19\uC740 \uD53C\uBD80\uC774\uC0C1\uC774 \uBC1C\uC0DD\uD560 \uC218 \uC788\uB2E4. \uD658\uC790\uB97C \uC2E0\uC911\uD788 \uAD00\uCC30\uD558\uACE0, \uB9CC\uC77C \uC774\uB7F0 \uC99D\uC0C1\uC774 \uBC1C\uC0DD\uD558\uBA74, \uD22C\uC5EC\uB97C \uC911\uB2E8\uD558\uACE0, \uC801\uC808\uD55C \uC870\uCE58\uB97C \uCDE8\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>(5) \uAE09\uC131 \uC2E0\uBD80\uC804 : \uAE09\uC131 \uC2E0\uBD80\uC804\uC774 \uBC1C\uC0DD\uD560 \uC218 \uC788\uB2E4. \uD658\uC790\uB97C \uC2E0\uC911\uD788 \uAD00\uCC30\uD558\uACE0, \uB9CC\uC77C \uC774\uB7F0 \uC774\uC0C1\uC774 \uAD00\uCC30\uB418\uBA74 \uC989\uC2DC \uD22C\uC5EC\uB97C \uC911\uB2E8\uD558\uACE0 \uC801\uC808\uD55C \uC870\uCE58\uB97C \uCDE8\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>(6) \uBC31\uD608\uAD6C \uAC10\uC18C, \uD608\uC18C\uD310 \uAC10\uC18C : \uBC31\uD608\uAD6C \uAC10\uC18C\uC640 \uD608\uC18C\uD310 \uAC10\uC18C\uAC00 \uBC1C\uC0DD\uD560 \uC218 \uC788\uB2E4. \uD658\uC790\uB97C \uC2E0\uC911\uD788 \uAD00\uCC30\uD558\uACE0, \uB9CC\uC77C \uC774\uB7F0 \uC774\uC0C1\uC774 \uAD00\uCC30\uB418\uBA74, \uCE58\uB8CC \uC911\uB2E8\uACFC \uAC19\uC740 \uC801\uC808\uD55C \uC870\uCE58\uB97C \uCDE8\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>(7) \uC815\uC2E0\uC2E0\uACBD\uACC4 \uC99D\uD6C4\uAD70 : \uC815\uC2E0\uC2E0\uACBD \uC99D\uC0C1(\uC758\uC2DD\uC7A5\uC560, \uC774\uC0C1\uD589\uB3D9, \uC12C\uB9DD, \uD658\uAC01, \uB9DD\uC0C1, \uACBD\uB828)\uC774 \uB098\uD0C0\uB0A0 \uC218 \uC788\uB2E4. \uB9CC\uC77C \uC774\uC0C1\uC774 \uAD00\uCC30\uB418\uBA74, \uD22C\uC5EC\uB97C \uC911\uB2E8\uD574\uC57C \uD55C\uB2E4. \uD658\uC790\uB97C \uC2E0\uC911\uD788 \uAD00\uCC30\uD558\uACE0, \uAC01\uAC01\uC758 \uC99D\uC0C1\uC5D0 \uB530\uB77C \uC801\uC808\uD55C \uC870\uCE58\uB97C \uCDE8\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>(8) \uCD9C\uD608 \uB300\uC7A5\uC5FC : \uCD9C\uD608 \uB300\uC7A5\uC5FC\uC774 \uBC1C\uC0DD\uD560 \uC218 \uC788\uB2E4. \uB9CC\uC77C \uD608\uBCC0\uACFC \uAC19\uC740 \uC774\uC0C1\uC774 \uAD00\uCC30\uB418\uBA74, \uD22C\uC5EC\uB97C \uC911\uB2E8\uD558\uACE0, \uD658\uC790\uC5D0\uAC8C \uC801\uC808\uD55C \uC870\uCE58\uB97C \uCDE8\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>5) \uAE30\uD0C0 \uC774\uC0C1\uBC18\uC751\r\n

<\/P>\uC774 \uC678 \uC774 \uC57D\uC758 \uD22C\uC5EC \uD6C4 \uBCF4\uACE0\uB41C \uC774\uC0C1\uBC18\uC751\uC740 \uB2E4\uC74C\uACFC \uAC19\uC73C\uBA70, \uC774\uB7EC\uD55C \uC774\uC0C1\uBC18\uC751\uC774 \uD655\uC778\uB418\uBA74 \uC99D\uC0C1\uC5D0 \uB530\uB77C \uD22C\uC5EC \uC911\uB2E8\uACFC \uAC19\uC740 \uC801\uC808\uD55C \uCC98\uCE58\uB97C \uD55C\uB2E4.\r\n

<\/P>\r\n[&C2]*)<\/SUP> \uBE48\uB3C4\uB97C \uACC4\uC0B0\uD560 \uC218 \uC5C6\uB294 \uC790\uBC1C\uC801 \uBCF4\uACE0\uB294 \uBE48\uB3C4\uBD88\uBA85\uC73C\uB85C \uBD84\uB958\uB418\uC5C8\uC74C.\r\n

<\/P>6) 1\uC138 \uC774\uC0C1 \uC18C\uC544\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uBC0F \uC608\uBC29 : \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uC784\uC0C1\uC5D0 \uCC38\uC5EC\uD55C \uC18C\uC544 1,480\uBA85(1 \uFF5E 12\uC138 \uAC74\uAC15\uD55C \uC18C\uC544\uC640 6 \uFF5E 12\uC138\uC758 \uC18C\uC544\uCC9C\uC2DD \uD658\uC790)\uC758 \uC18C\uC544 \uD658\uC790 \uC911 \uCD1D 858\uBA85\uC758 \uD658\uC790\uAC00 \uC774 \uC57D \uD604\uD0C1\uC561\uC744 \uD22C\uC5EC \uBC1B\uC558\uB2E4. \uC790\uC5F0\uC801\uC73C\uB85C \uC778\uD50C\uB8E8\uC5D4\uC790\uC5D0 \uAC10\uC5FC\uB418\uC5B4 \uCE58\uB8CC \uBAA9\uC801\uC73C\uB85C \uC774 \uC57D\uC744 \uD22C\uC5EC(n = 858)\uD55C 1 \uFF5E 12\uC138 \uC18C\uC544\uC5D0\uC11C 1 % \uC774\uC0C1 \uBC1C\uC0DD\uD588\uACE0 \uC704\uC57D(n = 622)\uC5D0 \uBE44\uD574 \uBC1C\uC0DD\uB960\uC774 1 % \uC774\uC0C1 \uB192\uC558\uB358 \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\uC740 \uAD6C\uD1A0(\uC774 \uC57D \uD22C\uC5EC\uAD70 16 %, \uC704\uC57D\uD22C\uC5EC\uAD70 8 %)\uC600\uB2E4. \uC9D1\uC548\uC5D0\uC11C \uB178\uCD9C \uD6C4 \uC608\uBC29 \uC694\uBC95(post-exposure prophylaxis) \uC5F0\uAD6C(n = 99)\uC640 \uBCC4\uB3C4\uC758 6\uC8FC \uC18C\uC544 \uC608\uBC29 \uC5F0\uAD6C(n = 49)\uC5D0\uC11C 1\uC77C 1\uD68C \uAD8C\uC7A5\uC6A9\uB7C9\uC744 \uD22C\uC5EC\uD55C 148\uBA85\uC758 \uC18C\uC544 \uC911 \uAC00\uC7A5 \uD754\uD558\uAC8C \uBC1C\uC0DD\uD55C \uC57D\uBB3C\uC774\uC0C1\uBC18\uC751\uC740 \uAD6C\uD1A0\uC600\uB2E4(\uC774 \uC57D \uD22C\uC5EC \uAD70 8 %, \uC608\uBC29\uC694\uBC95\uC744 \uC2E4\uC2DC\uD558\uC9C0 \uC54A\uC740 \uAD70 2 %). \uC774\uC0C1\uC758 \uC784\uC0C1\uC2DC\uD5D8\uC5D0\uC11C \uC774 \uC57D\uC740 \uB0B4\uC57D\uC131\uC774 \uC88B\uC558\uACE0 \uBCF4\uACE0\uB41C \uC774\uC0C1\uBC18\uC751\uC740 \uAE30\uC874 \uC18C\uC544 \uCE58\uB8CC \uC5F0\uAD6C\uC5D0\uC11C \uAD00\uCC30\uB41C \uAC83\uACFC \uC77C\uCE58\uD558\uC600\uB2E4.\r\n

<\/P>\r\n[&C3]7) \uC18C\uC544 \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uC5F0\uAD6C \uC911 \uC774 \uC57D \uD22C\uC5EC \uC2DC 1 % \uBBF8\uB9CC\uC73C\uB85C \uBC1C\uC0DD\uD55C \uC774\uC0C1\uBC18\uC751\uC5D0\uB294 \uB9BC\uD504\uC808\uC5FC(\uC774 \uC57D \uD22C\uC5EC\uAD70 <1 %, \uC704\uC57D \uD22C\uC5EC\uAD70 1%), \uACE0\uB9C9\uC774\uC0C1(\uC774 \uC57D \uD22C\uC5EC\uAD70 <1 %, \uC704\uC57D \uD22C\uC5EC\uAD70 1 %)\uC774 \uC788\uC5C8\uB2E4.\r\n

<\/P>8) 2\uC8FC \uC774\uC0C1 1\uC138 \uBBF8\uB9CC \uC18C\uC544\uC5D0 \uB300\uD55C \uC790\uB8CC\r\n

<\/P>\uC774\uC0C1\uBC18\uC751\uC758 \uD3C9\uAC00\uB294 2\uAC1C\uC758 open label \uC5F0\uAD6C\uC5D0 \uADFC\uAC70\uD55C\uB2E4. \uC774 \uC5F0\uAD6C\uB294 \uC778\uD50C\uB8E8\uC5D4\uC790\uC5D0 \uAC10\uC5FC\uB41C 2\uC8FC\uB839 \uFF5E 1\uC138 \uBBF8\uB9CC \uC18C\uC544 135\uBA85(\uC218\uD0DC\uC5F0\uB839\uC774 36\uC8FC \uC774\uC0C1\uC778 \uBBF8\uC131\uC219\uC544 \uD3EC\uD568)\uC744 5\uC77C\uAC04 1\uC77C 2\uD68C\uC529 \uCCB4\uC911 kg\uB2F9 2 \uFF5E 3.5 mg\uC744 \uC774 \uC57D\uC5D0 \uB178\uCD9C\uC2DC\uCF30\uC744 \uB54C\uC758 \uC548\uC804\uC131 \uC790\uB8CC\uB97C \uD3EC\uD568\uD55C\uB2E4. \uC548\uC804\uC131 \uC591\uC0C1\uC740 \uC5F0\uAD6C\uB41C \uC5F0\uB839 \uBC94\uC704\uC5D0\uC11C \uC720\uC0AC\uD558\uC600\uC73C\uBA70, \uAD6C\uD1A0, \uC124\uC0AC \uBC0F \uAE30\uC800\uADC0 \uBC1C\uC9C4\uC774 \uAC00\uC7A5 \uD754\uD558\uAC8C \uBCF4\uACE0\uB41C \uC774\uC0C1\uBC18\uC751\uC774\uC5C8\uB2E4. 2\uC8FC \uFF5E 1\uC138 \uBBF8\uB9CC \uC18C\uC544\uC5D0\uC11C \uAD00\uCC30\uB41C \uC548\uC804\uC131 \uC591\uC0C1\uC740 1\uC138 \uC774\uC0C1 \uC131\uC778 \uBC0F \uCCAD\uC18C\uB144\uC5D0 \uB300\uD558\uC5EC \uD655\uB9BD\uB41C \uAC83\uACFC \uC77C\uCE58\uD558\uC600\uB2E4.\r\n

<\/P>9) \uBA74\uC5ED\uC7A5\uC560 \uD658\uC790\uC5D0\uC11C\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\r\n

<\/P>475\uBA85\uC758 \uBA74\uC5ED\uC7A5\uC560 \uD658\uC790(18\uBA85\uC758 \uC18C\uC544 \uD658\uC790 \uD3EC\uD568)\uAC00 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\uC5D0 \uB300\uD55C \uC784\uC0C1\uC2DC\uD5D8\uC5D0 \uCC38\uC5EC\uD558\uC600\uB2E4. \uC778\uD50C\uB8E8\uC5D4\uC790 \uC720\uD589\uAE30\uAC04 \uB3D9\uC548 \uC608\uBC29\uC744 \uC704\uD558\uC5EC 12\uC8FC \uB3D9\uC548 \uC774 \uC57D\uC744 \uD22C\uC5EC \uBC1B\uC740 13\uC138 \uC774\uC0C1\uC758 \uCCAD\uC18C\uB144 \uBC0F \uC131\uC778 \uBA74\uC5ED\uC7A5\uC560\uD658\uC790\uC5D0\uC11C \uC774\uC0C1\uBC18\uC751\uC740 \uAE30\uC874 \uC608\uBC29\uC5F0\uAD6C\uC5D0\uC11C \uAD00\uCC30\uB41C \uC774\uC0C1\uBC18\uC751\uACFC \uB3D9\uC77C\uD558\uC600\uB2E4.\r\n

<\/P>10) \uC2DC\uD310\uD6C4 \uACBD\uD5D8\r\n

<\/P>\uC774 \uC57D\uC758 \uC2DC\uD310\uD6C4 \uB2E4\uC74C\uACFC \uAC19\uC740 \uC774\uC0C1\uBC18\uC751\uC774\uBCF4\uACE0\uB418\uC5C8\uB2E4. \uB2E4\uC74C \uC774\uC0C1\uBC18\uC751\uC740 \uC815\uD655\uD55C \uC218\uB97C \uC54C \uC218 \uC5C6\uB294 \uC9D1\uB2E8\uC5D0\uC11C \uC790\uBC1C\uC801\uC73C\uB85C \uBCF4\uACE0\uB418\uC5C8\uAE30 \uB54C\uBB38\uC5D0 \uBE48\uB3C4 \uBC0F\/\uB610\uB294 \uC774 \uC57D\uACFC\uC758 \uC5F0\uAD00\uC131\uC744 \uD655\uB9BD\uD558\uAE30 \uC5B4\uB835\uB2E4.\r\n

<\/P>(1) \uD53C\uBD80 \uBC0F \uD53C\uD558\uC870\uC9C1 : \uD53C\uBD80\uC5FC, \uBC1C\uC9C4, \uC2B5\uC9C4, \uB450\uB4DC\uB7EC\uAE30, \uB2E4\uD615\uD64D\uBC18, \uC54C\uB808\uB974\uAE30 \uBC0F \uC544\uB098\uD544\uB77D\uC2DC\uC2A4 \uB610\uB294 \uC544\uB098\uD544\uB77D\uC2DC\uC2A4\uBAA8\uC591 \uBC18\uC751, \uC548\uBA74\uBD80\uC885, \uD53C\uBD80\uC810\uB9C9\uC548\uC99D\uD6C4\uAD70(\uC2A4\uD2F0\uBE10\uC2A4-\uC874\uC2A8 \uC99D\uD6C4\uAD70) \uBC0F \uB3C5\uC131\uD45C\uD53C\uAD34\uC0AC\uC6A9\uD574(\uB9AC\uC5D8\uC99D\uD6C4\uAD70)\uC640 \uAC19\uC740 \uACFC\uBBFC\uBC18\uC751\uC774 \uBCF4\uACE0\uB418\uC5C8\uB2E4.\r\n

<\/P>(2) \uAC04 \uBC0F \uB2F4\uB3C4\uACC4 : \uAC04\uC5FC \uBC0F \uAC04\uD6A8\uC18C \uC218\uCE58 \uC0C1\uC2B9\uC774 \uBCF4\uACE0\uB418\uC5C8\uB2E4.\r\n

<\/P>(3) \uC2EC\uD608\uAD00\uACC4 : \uBD80\uC815\uB9E5\r\n

<\/P>(4) \uC815\uC2E0\uC2E0\uACBD\uACC4 : \uBC1C\uC791, \uD63C\uB780\r\n

<\/P>(5) \uC704\uC7A5\uAD00\uACC4 : \uC704\uC7A5\uAD00 \uCD9C\uD608, \uCD9C\uD608\uC131 \uB300\uC7A5\uC5FC\r\n

<\/P>(6) \uB300\uC0AC : \uB2F9\uB1E8\uBCD1 \uC545\uD654\r\n

<\/P>(7) \uD608\uC561 : \uD638\uC0B0\uAD6C\uC99D\uAC00\uC99D, \uBC31\uD608\uAD6C\uAC10\uC18C\uC99D\r\n

<\/P>(8) \uAE30\uD0C0 : \uCDCC\uC7A5\uC5FC, \uD608\uAD00\uBD80\uC885, \uD6C4\uB450\uBD80\uC885, \uD600\uBD80\uC885, \uAE30\uAD00\uC9C0\uC5F0\uCD95, \uC548\uBA74\uBD80\uC885, \uD608\uB1E8 \uB4F1\uC774 \uBCF4\uACE0\uB418\uC5C8\uB2E4.\r\n

<\/P>(9) \uC77C\uBC18\uC801\uC73C\uB85C \uC778\uD50C\uB8E8\uC5D4\uC790\uC640 \uACE0\uC5F4\uC740 \uC774 \uC57D\uC744 \uD22C\uC5EC\uD558\uC9C0 \uC54A\uC558\uC5B4\uB3C4 \uC77C\uBD80 \uACBD\uC6B0 \uBD88\uBA74\uC99D, \uCC29\uB780, \uACBD\uB828, \uD658\uAC01\uACFC \uAC19\uC740 \uC911\uC99D \uC2E0\uACBD\uC815\uC2E0\uACC4 \uC7A5\uC560\uC640 \uAD00\uB828\uC774 \uC788\uB2E4. \uC774\uB7EC\uD55C \uC774\uC0C1\uBC18\uC751\uC774 \uC774 \uC57D\uC758 \uC2DC\uD310 \uD6C4 \uBCF4\uACE0\uB418\uC5C8\uC73C\uB098 \uC57D\uBB3C\uACFC\uC758 \uC5F0\uAD00\uC131\uC740 \uD655\uB9BD\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>11) \uAD6D\uB0B4\uC5D0\uC11C \uC7AC\uC2EC\uC0AC\uB97C \uC704\uD558\uC5EC 6\uB144 \uB3D9\uC548 3,130\uBA85\uC744 \uB300\uC0C1\uC73C\uB85C \uC2E4\uC2DC\uD55C \uC0AC\uC6A9\uC131\uC801\uC870\uC0AC\uACB0\uACFC \uC774\uC0C1\uBC18\uC751\uC758 \uBC1C\uD604\uC99D\uB840\uC728\uC740 \uC778\uACFC\uAD00\uACC4\uC640 \uC0C1\uAD00\uC5C6\uC774 0.93 %(29\uB840\/3,130\uB840)\uB85C \uBCF4\uACE0\uB418\uC5C8\uACE0, \uC774 \uC911 \uC774 \uC57D\uACFC \uC778\uACFC\uAD00\uACC4\uAC00 \uC788\uB294 \uAC83\uC73C\uB85C \uC870\uC0AC\uB41C \uAC83\uC740 0.67 %(21\uB840\/3,130\uB840)\uC774\uC5C8\uB2E4. \uAD6C\uC5ED\uC774 12\uB840\uB85C \uAC00\uC7A5 \uB9CE\uC558\uACE0, \uADF8 \uB2E4\uC74C\uC740 \uAD6C\uD1A0 4\uB840, \uC124\uC0AC 2\uB840\uC758 \uC21C\uC73C\uB85C \uB098\uD0C0\uB0AC\uC73C\uBA70, \uADF8 \uBC16\uC5D0 \uBCF5\uD1B5, \uC545\uBABD, \uC5B4\uC9C0\uB7FC, \uD53C\uBD80\uC5FC\uC774 \uAC01 1\uB840\uC529 \uBCF4\uACE0\uB418\uC5C8\uB2E4.\r\n

<\/P>12) \uAD6D\uB0B4 \uC2DC\uD310 \uD6C4 \uC774\uC0C1\uC0AC\uB840 \uBCF4\uACE0\uC790\uB8CC(1989-2016\uB1446\uC6D4)\uB97C \uD1A0\uB300\uB85C \uC2E4\uB9C8\uB9AC\uC815\uBCF4 \uBD84\uC11D\u00B7\uD3C9\uAC00 \uACB0\uACFC \uC0C8\uB85C \uD655\uC778\uB41C \uC774\uC0C1\uC0AC\uB840\uB294 \uB2E4\uC74C\uACFC \uAC19\uB2E4. \uB2E4\uB9CC, \uC774\uB85C\uC11C \uACE7 \uD574\uB2F9\uC131\uBD84\uACFC \uB2E4\uC74C\uC758 \uC774\uC0C1\uC0AC\uB840 \uAC04\uC5D0 \uC778\uACFC\uAD00\uACC4\uAC00 \uC785\uC99D\uB41C \uAC83\uC744 \uC758\uBBF8\uD558\uB294 \uAC83\uC740 \uC544\uB2C8\uB2E4.\r\n

<\/P>\u2981 \uC815\uC2E0\uACC4 : \uC218\uBA74\uC7A5\uC560\r\n

<\/P>5. \uC77C\uBC18\uC801 \uC8FC\uC758\r\n

<\/P>1) \uC774 \uC57D\uC740 \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC31\uC2E0\uC758 \uB300\uC6A9\uD488\uC774 \uC544\uB2C8\uB2E4. \uC774 \uC57D\uC758 \uC0AC\uC6A9\uC740 Center for Disease Controls Prevention Advisory Committee on Immunization Practices\uC758 \uC9C0\uCE68\uC5D0 \uB530\uB978 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\uC811\uC885\uC5D0 \uC601\uD5A5\uC744 \uBBF8\uCCD0\uC11C\uB294 \uC548 \uB41C\uB2E4.\r\n

<\/P>2) \uC785\uC6D0\uC744 \uC694\uD558\uB294 \uC704\uD5D8\uD55C \uC0C1\uD0DC\uC5D0 \uC788\uAC70\uB098 \uC2EC\uD558\uAC8C \uC548 \uC88B\uC740 \uC0C1\uD0DC\uC5D0 \uC788\uB294 \uD658\uC790\uC5D0 \uB300\uD55C \uCE58\uB8CC\uC815\uBCF4\uB294 \uC81C\uACF5\uB41C \uBC14 \uC5C6\uB2E4. \uB610\uD55C \uCE58\uB8CC\uACFC\uC815\uC744 \uBC18\uBCF5\uD558\uC600\uC744 \uB54C\uC758 \uC548\uC804\uC131 \uBC0F \uC720\uD6A8\uC131\uC5D0 \uB300\uD574 \uC5F0\uAD6C\uB41C \uBC14 \uC5C6\uB2E4. \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC\uC5D0 \uAD00\uD55C 3\uC0C1 \uC784\uC0C1\uC5F0\uAD6C\uC5D0\uC11C 6\uC8FC \uC774\uC0C1 \uC774 \uC57D\uC744 \uD22C\uC5EC\uD55C \uACBD\uD5D8\uC740 \uC5C6\uB2E4.\r\n

<\/P>3) \uBA74\uC5ED\uC7A5\uC560 \uD658\uC790\uC5D0\uC11C \uC778\uD50C\uB8E8\uC5D4\uC790 \uC720\uD589 \uAE30\uAC04 \uC911 \uC608\uBC29\uC744 \uC704\uD558\uC5EC \uCD5C\uB300 12\uC8FC\uAE4C\uC9C0 \uD22C\uC5EC\uC5D0 \uB300\uD558\uC5EC \uC548\uC804\uC131\uC774 \uD655\uBCF4\uB418\uC5C8\uB2E4. \uBA74\uC5ED \uC7A5\uC560 \uD658\uC790\uC5D0\uC11C \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC \uBC0F \uC608\uBC29\uC744 \uC704\uD55C \uC774 \uC57D\uC758 \uC720\uD6A8\uC131\uC740 \uBA85\uD655\uD558\uAC8C \uD655\uB9BD\uB418\uC5B4 \uC788\uC9C0 \uC54A\uB2E4.\r\n

<\/P>4) \uC99D\uC0C1 \uBC1C\uD604 40\uC2DC\uAC04 \uD6C4 \uCE58\uB8CC\uB97C \uC2DC\uC791\uD55C \uD658\uC790\uC5D0\uC11C \uC774 \uC57D\uC758 \uC720\uD6A8\uC131\uC740 \uD655\uB9BD\uB418\uC5B4 \uC788\uC9C0 \uC54A\uB2E4.\r\n

<\/P>5) \uC911\uC99D \uC138\uADE0\uAC10\uC5FC\uC740 \uC778\uD50C\uB8E8\uC5D4\uC790\uBAA8\uC591 \uC99D\uC0C1\uC73C\uB85C \uC2DC\uC791\uB420 \uC218 \uC788\uC73C\uBA70 \uC778\uD50C\uB8E8\uC5D4\uC790\uC640 \uAC19\uC774 \uC874\uC7AC\uD558\uAC70\uB098 \uB610\uB294 \uC778\uD50C\uB8E8\uC5D4\uC790\uAC00 \uC9C4\uD589\uB418\uB294 \uB3D9\uC548 \uD569\uBCD1\uC99D\uC73C\uB85C \uBC1C\uC0DD\uD560 \uC218 \uC788\uB2E4. \uC774 \uC57D\uC740 \uC774\uB7F0 \uD569\uBCD1\uC99D\uC744 \uC608\uBC29\uD560 \uC218 \uC5C6\uB2E4.\r\n

<\/P>6) \uB9CC\uC131 \uC2EC\uC7A5 \uC9C8\uD658\uC774\uB098 \uD638\uD761\uAE30 \uC9C8\uD658\uC744 \uAC00\uC9C4 \uD658\uC790\uC5D0 \uB300\uD55C \uC774 \uC57D\uC758 \uC720\uD6A8\uC131\uC740 \uD655\uB9BD\uB418\uC5B4 \uC788\uC9C0 \uC54A\uB2E4. \uC774\uB4E4 \uC9D1\uB2E8\uC744 \uB300\uC0C1\uC73C\uB85C \uC774 \uC57D\uACFC \uC704\uC57D\uC744 \uD22C\uC5EC\uD55C \uACBD\uC6B0 \uC774 \uC57D \uD22C\uC5EC\uAD70\uACFC \uC704\uC57D \uD22C\uC5EC\uAD70 \uC0AC\uC774\uC5D0 \uD569\uBCD1\uC99D \uBC1C\uC0DD\uC5D0 \uC788\uC5B4 \uC5B4\uB5A4 \uCC28\uC774\uB3C4 \uAD00\uCC30\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>7) \uD658\uC790\uB4E4\uC740 \uAC00\uB2A5\uD55C \uD55C \uB3C5\uAC10 \uC99D\uC0C1 \uCD08\uAE30\uC5D0 \uC774 \uC57D\uC744 \uC0AC\uC6A9\uD558\uB3C4\uB85D \uC9C0\uC2DC\uBC1B\uC544\uC57C \uD55C\uB2E4. \uC81C \uC2DC\uAC04\uC5D0 \uC57D\uC744 \uBCF5\uC6A9\uD558\uC9C0 \uBABB\uD55C \uACBD\uC6B0, \uB2E4\uC74C \uC608\uC815\uC2DC\uAC04\uACFC\uC758 \uAC04\uACA9\uC774 2\uC2DC\uAC04 \uC774\uB0B4\uC778 \uACBD\uC6B0\uB97C \uC81C\uC678\uD558\uACE0\uB294 \uAC00\uB2A5\uD55C \uBE68\uB9AC \uB204\uB77D\uB41C \uC6A9\uB7C9\uC744 \uBCF5\uC6A9\uD558\uC5EC\uC57C \uD558\uBA70, \uC774\uD6C4 \uC77C\uC815 \uC2DC\uAC04\uC5D0 \uBCF5\uC6A9\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>8) \uC790\uB3D9\uCC28 \uC6B4\uC804\uC774\uB098 \uAE30\uACC4\uC870\uC791 \uB4F1\uC5D0 \uBBF8\uCE58\uB294 \uC601\uD5A5\uC740 \uAD00\uCC30\uB418\uC9C0 \uC54A\uC558\uC73C\uB098, \uC778\uD50C\uB8E8\uC5D4\uC790\uC5D0 \uC758\uD55C \uC774\uB7EC\uD55C \uB2A5\uB825 \uC190\uC0C1 \uAC00\uB2A5\uC131\uC744 \uC720\uC758\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>6. \uC0C1\uD638\uC791\uC6A9\r\n

<\/P>1) \uC774 \uC57D\uC758 \uC57D\uB9AC \uBC0F \uC57D\uB3D9\uD559 \uC2DC\uD5D8 \uACB0\uACFC, \uC784\uC0C1\uC801\uC73C\uB85C \uC720\uC758\uC131 \uC788\uB294 \uC57D\uBB3C \uC0C1\uD638\uC791\uC6A9\uC740 \uC5C6\uC744 \uAC83\uC73C\uB85C \uC608\uC0C1\uB41C\uB2E4.\r\n

<\/P>2) \uC774 \uC57D\uC740 \uC8FC\uB85C \uAC04\uC5D0 \uC874\uC7AC\uD558\uB294 \uC5D0\uC2A4\uD130\uB77C\uC81C\uC5D0 \uC758\uD574 \uD65C\uC131\uD615\uC73C\uB85C \uC2E0\uC18D\uD558\uAC8C \uC804\uD658\uB41C\uB2E4. \uC5D0\uC2A4\uD130\uB77C\uC81C\uC5D0 \uB300\uD55C \uACBD\uC7C1\uC5D0 \uAE30\uCD08\uD55C \uC57D\uBB3C\uC0C1\uD638\uC791\uC6A9\uC740 \uBB38\uD5CC\uC5D0 \uAC70\uC758 \uBCF4\uACE0\uB418\uC5B4 \uC788\uC9C0 \uC54A\uB2E4. \uC774 \uC57D\uACFC \uD65C\uC131\uD615\uC758 \uB2E8\uBC31\uACB0\uD569\uC728\uC774 \uB0AE\uC544 \uC57D\uBB3C\uB300\uCCB4 \uC0C1\uD638\uC791\uC6A9\uC758 \uAC00\uB2A5\uC131\uB3C4 \uD76C\uBC15\uD558\uB2E4. \uC2DC\uD5D8\uAD00\uB0B4 \uC2E4\uD5D8\uC5D0 \uC758\uD558\uBA74, \uC774 \uC57D\uACFC \uD65C\uC131\uB300\uC0AC\uCCB4 \uBAA8\uB450 CYP-450 mixed-function oxidase\uB098 glucuronyl transferase\uC758 \uC791\uC6A9\uC744 \uBC1B\uC9C0 \uC54A\uC544, CYP-450 \uB3D9\uC885\uD6A8\uC18C \uAD00\uB828 \uC57D\uBB3C\uC0C1\uD638\uC791\uC6A9\uC740 \uC5C6\uC744 \uAC83\uC73C\uB85C \uD310\uB2E8\uB41C\uB2E4.\r\n

<\/P>3) \uACBD\uC7C1\uC801 \uC2E0\uC138\uB1E8\uAD00 \uBD84\uBE44\uC5D0 \uAD00\uB828\uB41C \uC57D\uBB3C\uB4E4\uC740 \uADF8 \uC57D\uBB3C\uB4E4\uC758 \uC548\uC804\uC5ED, \uD65C\uC131 \uB300\uC0AC\uCCB4\uC758 \uBC30\uC124 \uD2B9\uC131(\uC0AC\uAD6C\uC138 \uC5EC\uACFC \uBC0F \uC74C\uC774\uC628\uC131 \uC138\uB1E8\uAD00 \uBD84\uBE44), \uBC30\uC124\uB2A5\uC758 \uD2B9\uC131\uC73C\uB85C \uC778\uD558\uC5EC \uC784\uC0C1\uC801\uC73C\uB85C \uC911\uC694\uD55C \uC0C1\uD638\uC791\uC6A9\uC740 \uC5C6\uC744 \uAC83\uC73C\uB85C \uBCF4\uC774\uB098, \uB2A5\uB3D9 \uC2E0\uBC30\uC124\uC774 \uC774\uB8E8\uC5B4\uC9C0\uB294 \uC548\uC804\uC5ED\uC774 \uC881\uC740 \uC57D\uBB3C(\uC608, \uD074\uB85C\uB974\uD504\uB85C\uD30C\uBBF8\uB4DC, \uBA54\uD1A0\uD2B8\uB809\uC138\uC774\uD2B8, \uD398\uB2D0\uBD80\uD0C0\uC874)\uC740 \uBCD1\uC6A9 \uD22C\uC5EC\uC2DC \uC8FC\uC758\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>4) \uACBD\uAD6C\uC6A9 \uD53C\uC784\uC81C\uC640\uC758 \uC0C1\uD638\uC791\uC6A9\uC740 \uC791\uC6A9\uAE30\uC804 \uC0C1 \uADFC\uAC70\uAC00 \uC5C6\uB2E4.\r\n

<\/P>5) \uC704\uC758 \uC0B0\uC131\uB3C4\uB97C \uBC14\uAFB8\uB294 \uAC83\uC73C\uB85C \uC54C\uB824\uC9C4 \uC2DC\uBA54\uD2F0\uB518\uC740 CYP-450 \uB3D9\uC885\uD6A8\uC18C\uC5D0 \uB300\uD55C \uBE44\uD2B9\uC774\uC801\uC778 \uC800\uD574\uC81C\uB85C\uC11C \uC2E0\uC138\uB1E8\uAD00 \uBD84\uBE44\uC5D0\uC11C \uC5FC\uAE30\uC131 \uB610\uB294 \uC591\uC774\uC628\uC131 \uC57D\uBB3C\uACFC \uACBD\uC7C1\uD55C\uB2E4. \uC2DC\uBA54\uD2F0\uB518\uC740 \uC774 \uC57D \uB610\uB294 \uC774 \uC57D\uC758 \uD65C\uC131\uB300\uC0AC\uCCB4\uC758 \uD608\uC7A5 \uB18D\uB3C4\uC5D0 \uC601\uD5A5\uC744 \uBBF8\uCE58\uC9C0 \uC54A\uB294\uB2E4. \uADF8\uB7EC\uBBC0\uB85C \uC704\uC758 \uC0B0\uC131\uB3C4\uB97C \uBC14\uAFB8\uB294 \uC57D\uBB3C\uC774\uB098(\uC81C\uC0B0\uC81C) \uC704\uC640 \uAC19\uC740 \uB300\uC0AC\uACBD\uB85C\uB85C \uBC30\uC124\uB418\uB294 \uC57D\uBB3C\uACFC \uC784\uC0C1\uC801\uC73C\uB85C \uC911\uC694\uD55C \uC57D\uBB3C\uC0C1\uD638\uC791\uC6A9\uC740 \uC608\uC0C1\uB418\uC9C0 \uC54A\uC73C\uBA70, \uC81C\uC0B0\uC81C\uC640\uC758 \uC0C1\uD638\uC791\uC6A9\uC740 \uC0DD\uCCB4\uB0B4\uC5D0\uC11C \uC2DC\uD5D8\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>6) \uD504\uB85C\uBCA0\uB124\uC2DC\uB4DC\uB97C \uBCD1\uC6A9\uD55C \uACB0\uACFC, \uB2A5\uB3D9\uC801 \uC2E0\uC138\uB1E8\uAD00 \uBD84\uBE44\uC758 \uAC10\uC18C \uB54C\uBB38\uC5D0, \uD65C\uC131\uB300\uC0AC\uCCB4\uC5D0 \uB300\uD55C \uC804\uC2E0\uC801 \uC774\uC6A9\uB960\uC774 \uC57D 2\uBC30 \uC99D\uAC00\uD558\uC600\uC73C\uB098, \uC548\uC804\uC5ED\uC774 \uB113\uAE30 \uB54C\uBB38\uC5D0 \uC6A9\uB7C9\uC744 \uC870\uC808\uD560 \uD544\uC694\uB294 \uC5C6\uC5C8\uB2E4.\r\n

<\/P>7) \uC544\uBAA9\uC2DC\uC2E4\uB9B0\uACFC \uBCD1\uC6A9\uC2DC \uC11C\uB85C\uAC04\uC758 \uD608\uC7A5\uB18D\uB3C4\uB97C \uBCC0\uD654\uC2DC\uD0A4\uC9C0 \uC54A\uC558\uB2E4. \uC774\uB294 \uC74C\uC774\uC628\uC131 \uBC30\uC124 \uACBD\uB85C\uC5D0\uC11C \uAC70\uC758 \uACBD\uC7C1\uD558\uC9C0 \uC54A\uB294\uB2E4\uB294 \uAC83\uACFC \uC2E0\uC138\uB1E8\uAD00\uC744 \uD1B5\uD558\uC5EC \uBC30\uC124\uB418\uB294 \uB2E4\uB978 \uC720\uAE30\uC0B0(\uC608, \uC544\uC2A4\uD53C\uB9B0)\uACFC \uC911\uC694\uD55C \uACBD\uC7C1\uC744 \uD560 \uD655\uB960\uC774 \uB0AE\uB2E4\uB294 \uAC83\uC744 \uC758\uBBF8\uD55C\uB2E4.\r\n

<\/P>8) \uC544\uC138\uD2B8\uC544\uBBF8\uB178\uD39C\uACFC \uBCD1\uC6A9\uC2DC\uC5D0\uB3C4 \uC774 \uC57D\uACFC \uADF8 \uD65C\uC131 \uB300\uC0AC\uCCB4 \uBC0F \uC544\uC138\uD2B8\uC544\uBBF8\uB178\uD39C\uC758 \uD608\uC7A5\uB18D\uB3C4\uB294 \uBCC0\uD654\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>9) \uC774 \uC57D\uACFC(75 mg, 1\uC77C 2\uD68C 4\uC77C\uAC04 \uD22C\uC5EC) \uC544\uC2A4\uD53C\uB9B0 900 mg \uBCD1\uC6A9 \uD22C\uC5EC \uD6C4, \uC774 \uC57D\uC758 \uD65C\uC131 \uB300\uC0AC\uCCB4 \uBC0F \uC544\uC2A4\uD53C\uB9B0\uC758 \uC57D\uBB3C \uB3D9\uD0DC \uBCC0\uC218\uC5D0 \uC720\uC758\uD55C \uBCC0\uD654\uAC00 \uC5C6\uC5C8\uB2E4.\r\n

<\/P>10) \uC774 \uC57D\uACFC \uC218\uC0B0\uD654\uC54C\uB8E8\uBBF8\uB284, \uC218\uC0B0\uD654\uB9C8\uADF8\uB124\uC298\uC744 \uD3EC\uD568\uD55C \uC81C\uC0B0\uC81C \uB610\uB294 \uD0C4\uC0B0\uCE7C\uC298\uC744 \uD3EC\uD568\uD55C \uC81C\uC0B0\uC81C, \uC544\uC138\uD2B8\uC544\uBBF8\uB178\uD39C, \uC544\uC2A4\uD53C\uB9B0, \uC2DC\uBA54\uD2F0\uB518, \uC640\uB974\uD30C\uB9B0, \uB9AC\uB9CC\uD0C0\uB518\uC744 \uBCD1\uC6A9 \uD22C\uC5EC \uD6C4, \uC774 \uC57D \uBC0F \uD65C\uC131 \uB300\uC0AC\uCCB4\uC758 \uC57D\uBB3C \uB3D9\uD0DC \uBCC0\uC218\uC5D0 \uC720\uC758\uD55C \uBCC0\uD654\uAC00 \uC5C6\uC5C8\uB2E4.\r\n

<\/P>11) \uAE30\uC9C8\uC774 \uC2E0\uC138\uB1E8\uAD00\uC73C\uB85C \uBD84\uBE44\uB418\uB294 \uAC04\uC2DC\uD074\uB85C\uBE44\uB974\uC640\uC758 \uC0C1\uD638\uC791\uC6A9\uC774 \uC2DC\uD310\uD6C4 \uBCF4\uACE0\uB418\uC5C8\uB2E4.\r\n

<\/P>12) \u2162\uC0C1 \uC784\uC0C1\uC2DC\uD5D8\uC5D0\uC11C \uC774 \uC57D\uC744 ACE\uC800\uD574\uC81C(\uC5D0\uB0A0\uB77C\uD504\uB9B4, \uCE85\uD1A0\uD504\uB9B4), \uD2F0\uC544\uC9C0\uB4DC\uACC4 \uC774\uB1E8\uC81C(\uBCA4\uB4DC\uB85C\uD50C\uB8E8\uC544\uC9C0\uB4DC), \uD56D\uC0DD\uC81C(\uD398\uB2C8\uC2E4\uB9B0, \uC138\uD314\uB85C\uC2A4\uD3EC\uB9B0, \uC544\uC9C0\uD2B8\uB85C\uB9C8\uC774\uC2E0, \uC5D0\uB9AC\uD2B8\uB85C\uB9C8\uC774\uC2E0, \uB3C5\uC2DC\uC0AC\uC774\uD074\uB9B0), H2 \uC218\uC6A9\uCCB4 \uCC28\uB2E8\uC81C(\uB77C\uB2C8\uD2F0\uB518, \uC2DC\uBA54\uD2F0\uB518), \uBCA0\uD0C0\uCC28\uB2E8\uC81C(\uD504\uB85C\uD504\uB77C\uB180\uB864), \uC794\uD2F4\uB958(\uD14C\uC624\uD544\uB9B0), \uAD50\uAC10\uC2E0\uACBD\uD765\uBD84\uC81C(\uC218\uB3C4\uC5D0\uD398\uB4DC\uB9B0), \uC544\uD3B8\uB958(\uCF54\uB370\uC778), \uBD80\uC2E0\uD53C\uC9C8\uD638\uB974\uBAAC\uC81C, \uD761\uC785\uD615 \uAE30\uAD00\uC9C0\uD655\uC7A5\uC81C, \uC9C4\uD1B5\uC81C(\uC544\uC2A4\uD53C\uB9B0, \uC774\uBD80\uD504\uB85C\uD39C, \uC544\uC138\uD2B8\uC544\uBBF8\uB178\uD39C) \uB4F1 \uD1B5\uC0C1 \uC0AC\uC6A9\uB418\uB294 \uC57D\uBB3C\uACFC \uD568\uAED8 \uD22C\uC5EC\uD558\uC5EC\uB3C4 \uC774\uC0C1\uBC18\uC751\uC758 \uC885\uB958\uB098 \uBE48\uB3C4\uC5D0\uB294 \uBCC0\uD568\uC774 \uC5C6\uC5C8\uB2E4.\r\n

<\/P>13) \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC31\uC2E0 : \uBE44\uAC15\uB0B4 \uC0DD\uC57D\uB3C5\uD654 \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC31\uC2E0(LAIV)\uACFC \uC774 \uC57D\uC758 \uB3D9\uC2DC \uC0AC\uC6A9\uC5D0 \uB300\uD55C \uD3C9\uAC00\uAC00 \uB418\uC9C0 \uC54A\uC558\uB2E4. \uC774\uB7EC\uD55C \uC81C\uC81C \uAC04\uC5D0 \uC7A0\uC7AC\uC801 \uAC04\uC12D \uB54C\uBB38\uC5D0, \uC758\uD559\uC801\uC73C\uB85C \uC785\uC99D\uB41C \uACBD\uC6B0\uB97C \uC81C\uC678\uD558\uACE0 LAIV\uB97C \uC774 \uC57D \uD22C\uC5EC \uC804 2\uC8FC \uC774\uB0B4 \uB610\uB294 \uC774 \uC57D \uD22C\uC5EC \uD6C4 48\uC2DC\uAC04 \uC774\uB0B4\uC5D0 \uD22C\uC5EC\uD574\uC11C\uB294 \uC548\uB41C\uB2E4. \uC0DD\uBC31\uC2E0 \uBC14\uC774\uB7EC\uC2A4\uC758 \uBCF5\uC81C\uB97C \uC5B5\uC81C\uD558\uB294 \uD56D\uBC14\uC774\uB7EC\uC2A4 \uC57D\uBB3C\uC5D0 \uB300\uD55C \uC7A0\uC7AC\uC801 \uAC04\uC12D \uAC00\uB2A5\uC131 \uACE0\uB824\uAC00 \uC99D\uAC00\uB418\uACE0 \uC788\uB2E4. 3\uAC00 \uBD88\uD65C\uC131\uD654 \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC31\uC2E0\uC740 \uC774 \uC57D \uC0AC\uC6A9\uACFC \uC5F0\uAD00\uD558\uC5EC \uC544\uBB34 \uB54C\uB098 \uD22C\uC5EC\uD560 \uC218 \uC788\uB2E4.\r\n

<\/P>7. \uC784\uBD80 \uBC0F \uC218\uC720\uBD80\uC5D0 \uB300\uD55C \uD22C\uC5EC\r\n

<\/P>1) \uCD9C\uC0DD \uC804\u00B7\uD6C4 \uBC1C\uC0DD \uBC0F \uBAA8\uCCB4\uAE30\uB2A5\uC2DC\uD5D8\uC5D0\uC11C \uB7AB\uD2B8\uC5D0 1,500 mg\/kg\/day \uD22C\uC5EC\uC2DC \uBD84\uB9CC\uC2DC\uAC04\uC774 \uC9C0\uC5F0\uB418\uC5C8\uACE0, \uCD9C\uC0DD\uD6C4 4\uC77C\uC9F8 \uCD9C\uC0DD\uC790\uC218\uAC00 \uAC10\uC18C\uB418\uC5C8\uB2E4. \uB7AB\uD2B8\uC640 \uD1A0\uB07C\uC5D0 \uB300\uD55C \uC0DD\uC2DD\uB3C5\uC131\uC2E4\uD5D8 \uACB0\uACFC, \uAE30\uD615\uBC1C\uC0DD\uC740 \uAD00\uCC30\uB418\uC9C0 \uC54A\uC558\uB2E4. \uB7AB\uD2B8\uC5D0\uC11C\uC758 \uC218\uD0DC\uB2A5\uACFC \uC0DD\uC2DD\uB2A5 \uC2E4\uD5D8\uACB0\uACFC, \uC2E4\uD5D8\uD588\uB358 \uBAA8\uB4E0 \uC6A9\uB7C9\uC5D0\uC11C \uC218\uD0DC\uB2A5\uC5D0 \uB300\uD55C \uC601\uD5A5\uC740 \uB098\uD0C0\uB098\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>2) \uB7AB\uD2B8\uC640 \uD1A0\uB07C\uC5D0\uC11C \uD0DC\uC790\uC5D0 \uB300\uD55C \uC57D\uBB3C \uB178\uCD9C\uC740 \uBAA8\uCCB4\uC758 \uB178\uCD9C\uACFC \uBE44\uAD50\uD558\uC5EC \uC57D 15 \uFF5E 20 %\uC774\uC5C8\uB2E4. \uD604\uC7AC, \uC774 \uC57D\uC744 \uD22C\uC5EC\uD55C \uC784\uBD80\uC5D0 \uB300\uD55C \uC790\uB8CC\uAC00 \uBD88\uCDA9\uBD84\uD558\uC5EC \uC774 \uC57D\uC774 \uD0DC\uC544 \uAE30\uD615\uC774\uB098 \uD0DC\uC544\uB3C5\uC131\uC744 \uC77C\uC73C\uD0AC \uAC00\uB2A5\uC131\uC774 \uC788\uB294\uC9C0\uB294 \uD310\uB2E8\uD560 \uC218 \uC5C6\uB2E4. \uADF8\uB7EC\uBBC0\uB85C \uC784\uBD80 \uB610\uB294 \uC784\uC2E0\uD558\uACE0 \uC788\uC744 \uAC00\uB2A5\uC131\uC774 \uC788\uB294 \uC5EC\uC131\uC5D0 \uC774 \uC57D\uC744 \uC0AC\uC6A9\uD560 \uACBD\uC6B0\uC5D0\uB294, \uCE58\uB8CC\uC0C1\uC758 \uC720\uC775\uC131\uC774 \uC704\uD5D8\uC131\uC744 \uC0C1\uD68C\uD558\uC5EC\uC57C \uD55C\uB2E4.\r\n

<\/P>3) \uC784\uBD80\uC5D0\uC11C \uC774 \uC57D \uC0AC\uC6A9\uC5D0 \uAD00\uD55C \uC784\uC0C1\uC5F0\uAD6C\uB294 \uC5C6\uC9C0\uB9CC, \uC2DC\uD310\uD6C4 \uC870\uC0AC \uBC0F \uAD00\uCC30\uC5F0\uAD6C \uBCF4\uACE0\uB97C \uD1B5\uD55C \uC81C\uD55C\uB41C \uC5F0\uAD6C\uAC00 \uC788\uB2E4. \uC774 \uB370\uC774\uD130\uB97C \uB3D9\uBB3C\uC2E4\uD5D8\uACFC \uACB0\uD569\uD558\uC5EC \uBD84\uC11D\uD55C \uACB0\uACFC \uC784\uC2E0, \uBC30\uC544\/\uD0DC\uC544, \uCD9C\uC0DD\uD6C4 \uBC1C\uB2EC\uACFC \uAD00\uB828\uD558\uC5EC \uC9C1\uC811\uC801 \uB610\uB294 \uAC04\uC811\uC801\uC778 \uC704\uD574\uC791\uC6A9\uC774 \uB098\uD0C0\uB098\uC9C0 \uC54A\uC558\uB2E4. \uC548\uC804\uC131 \uC815\uBCF4, \uC720\uD589 \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4 \uADE0\uC8FC\uC758 \uBCD1\uC6D0\uC131, \uC784\uBD80\uC758 \uC0C1\uD0DC\uB97C \uACE0\uB824\uD55C \uD6C4, \uC774 \uC57D\uC744 \uD22C\uC5EC\uD560 \uC218 \uC788\uB2E4\r\n

<\/P>4) \uC218\uC720\uAE30 \uB7AB\uD2B8\uC5D0\uC11C, \uC774 \uC57D\uACFC \uADF8 \uD65C\uC131\uB300\uC0AC\uCCB4\uAC00 \uC720\uC999\uB85C \uBD84\uBE44\uB418\uC5C8\uB2E4. \uB3D9\uBB3C\uC2E4\uD5D8 \uC790\uB8CC\uB85C\uBD80\uD130 \uC774 \uC57D\uC740 0.01 mg\/day, \uD65C\uC131\uB300\uC0AC\uCCB4\uD615\uC740 0.3 mg\/day\uC815\uB3C4 \uBD84\uBE44\uB420 \uAC83\uC73C\uB85C \uC608\uCE21\uB41C\uB2E4. \uC774 \uC57D\uC744 \uBCF5\uC6A9\uD55C \uC218\uC720\uBD80\uC758 \uBAA8\uC720\uB97C \uC12D\uCDE8\uD55C \uC601\uC544, \uBAA8\uC720\uC5D0\uC11C \uC774 \uC57D\uC758 \uAC80\uCD9C\uC5EC\uBD80\uC5D0 \uAD00\uD55C \uC815\uBCF4\uB294 \uB9E4\uC6B0 \uC81C\uD55C\uC801\uC774\uB2E4. \uC774 \uC81C\uD55C\uB41C \uB370\uC774\uD130\uB294 \uC774 \uC57D\uACFC \uADF8 \uD65C\uC131\uB300\uC0AC\uCCB4\uAC00 \uBAA8\uC720\uB85C \uBD84\uBE44\uB41C\uB2E4\uB294 \uC810\uC744 \uBCF4\uC5EC\uC8FC\uC5C8\uC73C\uB098, \uADF8 \uC591\uC774 \uC801\uACE0 \uCE58\uB8CC\uC6A9\uB7C9\uBCF4\uB2E4 \uC800\uC6A9\uB7C9\uC73C\uB85C \uB098\uD0C0\uB0AC\uB2E4. \uC774\uB7EC\uD55C \uC815\uBCF4, \uC720\uD589 \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4 \uADE0\uC8FC\uC758 \uBCD1\uC6D0\uC131, \uC218\uC720\uBD80\uC758 \uC0C1\uD0DC \uB4F1\uC744 \uACE0\uB824\uD558\uC5EC \uBA85\uBC31\uD55C \uCE58\uB8CC\uC0C1\uC758 \uC720\uC775\uC131\uC774 \uC704\uD5D8\uC131\uC744 \uC0C1\uD68C\uD558\uB294 \uACBD\uC6B0, \uC218\uC720\uBD80\uC5D0\uAC8C \uC774 \uC57D \uD22C\uC5EC\uB97C \uACE0\uB824\uD560 \uC218 \uC788\uB2E4.\r\n

<\/P>8. \uC18C\uC544\uC5D0 \uB300\uD55C \uD22C\uC5EC\r\n

<\/P>\uC774 \uC57D\uC740 1\uC138 \uBBF8\uB9CC\uC758 \uC18C\uC544\uC5D0 \uB300\uD55C \uC720\uD6A8\uC131\uC774 \uD655\uB9BD\uB418\uC5B4 \uC788\uC9C0 \uC54A\uB2E4. \uC57D\uB3D9\uD559 \uB370\uC774\uD130\uC5D0 \uB530\uB974\uBA74 2\uC8FC~12\uAC1C\uC6D4 \uC18C\uC544\uC5D0\uAC8C \uC774 \uC57D 3mg\/kg\uC744 1\uC77C 2\uD68C \uD22C\uC5EC\uD558\uC600\uC744 \uB54C, \uC784\uC0C1\uC801 \uC720\uD6A8\uC131\uC774 \uC608\uC0C1\uB418\uB294 \uC804\uAD6C\uC57D\uBB3C \uBC0F \uD65C\uC131\uB300\uC0AC\uCCB4\uC758 \uD608\uC911\uB18D\uB3C4\uB97C \uBCF4\uC600\uC73C\uBA70 1\uC138 \uC774\uC0C1 \uC18C\uC544 \uBC0F \uC131\uC778\uACFC \uB3D9\uB4F1\uD55C \uC548\uC804\uC131 \uD504\uB85C\uD544\uC744 \uB098\uD0C0\uB0C8\uB2E4. \uC778\uD50C\uB8E8\uC5D4\uC790 \uCE58\uB8CC\uC5D0 \uC788\uC5B4 2\uC8FC \uBBF8\uB9CC\uC758 \uC2E0\uC0DD\uC544\uC5D0 \uB300\uD55C \uC774 \uC57D\uC758 \uC548\uC804\uC131 \uBC0F \uC720\uD6A8\uC131\uC740 \uC5F0\uAD6C\uB418\uC9C0 \uC54A\uC558\uC73C\uBA70, \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\uC5D0 \uC788\uC5B4 1\uC138 \uBBF8\uB9CC\uC758 \uC18C\uC544\uC5D0 \uB300\uD55C \uC774 \uC57D\uC758 \uC548\uC804\uC131 \uBC0F \uC720\uD6A8\uC131\uC740 \uC5F0\uAD6C\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>9. \uACE0\uB839\uC790\uC5D0 \uB300\uD55C \uD22C\uC5EC\r\n

<\/P>\uACE0\uB839\uC790\uC5D0 \uB300\uD55C \uC784\uC0C1 \uC790\uB8CC\uB294 \uC81C\uD55C\uC801\uC774\uB098, \uC57D\uBB3C\uB178\uCD9C\uACFC \uB0B4\uC57D\uC131\uC744 \uACE0\uB824\uD560 \uB54C, \uC6A9\uB7C9\uC870\uC808\uC740 \uD544\uC694\uD558\uC9C0 \uC54A\uB2E4. \uACE0\uB839\uC790\uB4E4\uC740 \uC885\uC885 \uC2E0\uCCB4\uC801 \uAE30\uB2A5(\uC2E0\uAE30\uB2A5, \uAC04\uAE30\uB2A5 \uB4F1)\uC774 \uAC10\uC18C\uB418\uACE0, \uC5EC\uB7EC \uC9C0\uBCD1\uC744 \uC553\uAE30 \uC26C\uC6B0\uBBC0\uB85C \uC774 \uC57D \uD22C\uC5EC\uC2DC \uD658\uC790\uB97C \uC8FC\uC758 \uAE4A\uAC8C \uAD00\uCC30\uD558\uB3C4\uB85D \uD55C\uB2E4.\r\n

<\/P>10. \uACFC\uB7C9\uD22C\uC5EC\uC2DC\uC758 \uCC98\uCE58\r\n

<\/P>\uC784\uC0C1\uC2DC\uD5D8 \uBC0F \uC2DC\uD310\uD6C4 \uACBD\uD5D8\uC5D0\uC11C \uACFC\uB7C9 \uD22C\uC5EC\uB41C \uC0AC\uB840\uAC00 \uBCF4\uACE0\uB418\uC5C8\uC73C\uBA70 \uB300\uBD80\uBD84\uC758 \uACBD\uC6B0 \uC774\uC0C1\uBC18\uC751\uC774 \uBCF4\uACE0\uB418\uC9C0 \uC54A\uC558\uB2E4. \uACFC\uB7C9\uD22C\uC5EC \uD6C4 \uBCF4\uACE0\uB41C \uC774\uC0C1\uBC18\uC751\uC740 \uC774 \uC57D\uC744 \uC6A9\uBC95\uC6A9\uB7C9\uB300\uB85C \uD22C\uC5EC\uD558\uC600\uC744 \uB54C\uC758 \uC774\uC0C1\uBC18\uC751\uACFC \uADF8 \uC720\uD615 \uBC0F \uBE48\uB3C4\uAC00 \uC720\uC0AC\uD558\uC600\uB2E4(\uC774\uC0C1\uBC18\uC751\uD56D \uCC38\uACE0).\r\n

<\/P>11. \uBCF4\uAD00 \uBC0F \uCDE8\uAE09\uC0C1\uC758 \uC8FC\uC758\uC0AC\uD56D\r\n

<\/P>1) \uC5B4\uB9B0\uC774\uC758 \uC190\uC774 \uB2FF\uC9C0 \uC54A\uB294 \uACF3\uC5D0 \uBCF4\uAD00\uD55C\uB2E4.\r\n

<\/P>2) \uB2E4\uB978 \uC6A9\uAE30\uC5D0 \uBC14\uAFB8\uC5B4 \uB123\uB294 \uAC83\uC740 \uC0AC\uACE0\uC758 \uC6D0\uC778\uC774 \uB418\uAC70\uB098 \uD488\uC9C8 \uC720\uC9C0 \uBA74\uC5D0\uC11C \uBC14\uB78C\uC9C1\uD558\uC9C0 \uC54A\uC73C\uBBC0\uB85C \uC774\uB97C \uC8FC\uC758\uD55C\uB2E4.\r\n

<\/P>12. \uC758\uC57D\uD488\uB3D9\uB4F1\uC131\uC2DC\uD5D8 \uC815\uBCF4\r\n

<\/P>13. \uAE30\uD0C0\r\n

<\/P>1) \uC77C\uBCF8\uC5D0\uC11C\uC758 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\uC5D0 \uAD00\uD55C \u2162\uC0C1 \uC784\uC0C1\uC5F0\uAD6C\uC5D0\uC11C \uB2F9\uB1E8\uBCD1 \uC545\uD654\uAC00 \uD55C \uAC74 \uBCF4\uACE0\uB418\uC5C8\uC73C\uBA70, \uD574\uC678\uC5D0\uC11C \uC2DC\uD589\uB41C \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29\uC5D0 \uAD00\uD55C \u2162\uC0C1 \uC784\uC0C1\uC5F0\uAD6C\uC5D0\uC11C\uB294 \uB2F9 \uB300\uC0AC \uC7A5\uC560\uB97C \uAC16\uB294 \uD658\uC790\uC5D0\uC11C \uB2F9\uB1E8\uBCD1 \uC545\uD654 \uB610\uB294 \uACE0\uD608\uB2F9\uC99D 7\uAC74\uC774 \uBCF4\uACE0\uB418\uC5C8\uB2E4. \uADF8\uB7EC\uB098 \uC784\uC0C1 \uC6A9\uB7C9\uC758 100\uBC30\uB97C \uD22C\uC5EC\uD55C \uBE44\uC784\uC0C1 \uC2DC\uD5D8\uC5D0\uC11C \uB2F9 \uB300\uC0AC \uC5B5\uC81C\uB294 \uAD00\uCC30\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>2) \uBC14\uC774\uB7EC\uC2A4 \uB0B4\uC131\r\n

<\/P>\u2460 \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC5D0 \uB300\uD55C \uB0B4\uC131 \uB610\uB294 \uAC10\uC18C\uB41C \uBBFC\uAC10\uC131\uC744 \uC9C0\uB2CC \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4\uC758 \uBC1C\uD604\uAC00\uB2A5\uC131\uC774 \uC784\uC0C1\uC2DC\uD5D8\uC744 \uD1B5\uD574 \uD3C9\uAC00\uB418\uC5C8\uB2E4. \uC624\uC140\uD0C0\uBBF8\uBE44\uB974 \uB0B4\uC131 \uBC14\uC774\uB7EC\uC2A4 \uBCF4\uADE0\uC790\uB4E4\uC740 \uBAA8\uB450 \uC77C\uC2DC\uC801\uC774\uC5C8\uACE0, \uBC14\uC774\uB7EC\uC2A4\uAC00 \uC815\uC0C1\uC801\uC73C\uB85C \uC81C\uAC70\uB418\uC5C8\uC73C\uBA70, \uAE30\uC800 \uC99D\uC0C1\uC758 \uC545\uD654\uB3C4 \uAD00\uCC30\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>\r\n[&C4]* \uC804\uCCB4 \uC720\uC804\uD615 \uBD84\uC11D\uC740 \uBAA8\uB4E0 \uC2DC\uD5D8\uC5D0\uC11C \uC218\uD589\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>\uBA74\uC5ED\uB825\uC774 \uC788\uB294 \uD658\uC790\uB97C \uB300\uC0C1\uC73C\uB85C Post-exposure(7\uC77C), household contacts post-exposure(10\uC77C), \uACC4\uC808\uC801 \uC778\uD50C\uB8E8\uC5D4\uC790 \uC608\uBC29(42\uC77C)\uC5D0 \uB300\uD574 \uC2E4\uC2DC\uB41C \uC784\uC0C1\uC2DC\uD5D8\uC5D0\uC11C, \uC774 \uC57D \uD22C\uC57D\uACFC \uAD00\uB828\uB41C \uC57D\uC81C\uB0B4\uC131 \uBC1C\uD604\uC5D0 \uB300\uD55C \uC99D\uAC70\uB294 \uC5C6\uC5C8\uB2E4. \uBA74\uC5ED\uB825\uC774 \uC800\uD558\uB41C \uD658\uC790\uC5D0\uC11C 12\uC8FC \uC608\uBC29 \uC2DC\uD5D8 \uB3D9\uC548 \uB0B4\uC131\uC740 \uAD00\uCC30\uB418\uC9C0 \uC54A\uC558\uB2E4.\r\n

<\/P>\u2461 \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC5D0 \uB178\uCD9C\uB41C \uC801 \uC5C6\uB294 \uD658\uC790\uB85C\uBD80\uD130 \uBD84\uB9AC\uD55C \uC778\uD50C\uB8E8\uC5D4\uC790 A, B\uC5D0\uC11C \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC5D0 \uB300\uD55C \uBBFC\uAC10\uC131 \uAC10\uC18C\uC640 \uC5F0\uAD00\uB41C \uC790\uC5F0 \uB3CC\uC5F0\uBCC0\uC774\uAC00 in vitro\uC5D0\uC11C \uAD00\uCC30\uB418\uC5C8\uB2E4. 2008\uB144 \uC720\uB7FD\uC5D0\uC11C, \uC21C\uD658\uD558\uB294 H1N1 \uC778\uD50C\uB8E8\uC5D4\uC790\uC758 99% \uC774\uC0C1\uC5D0\uC11C \uC624\uC140\uD0C0\uBBF8\uBE44\uB974 \uB0B4\uC131\uACFC \uAD00\uB828\uC788\uB294 H275Y \uCE58\uD658\uC774 \uBC1C\uACAC\uB418\uC5C8\uB2E4. \uBC18\uBA74\uC5D0, 2009 H1N1 \uC778\uD50C\uB8E8\uC5D4\uC790(\u201C\uB3FC\uC9C0 \uB3C5\uAC10\u201D)\uB294 \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC5D0 \uB300\uD574 \uAC70\uC758 \uADE0\uC77C\uD558\uAC8C \uBBFC\uAC10\uD558\uC600\uB2E4. \uC624\uC140\uD0C0\uBBF8\uBE44\uB974 \uCE58\uB8CC\uB97C \uBC1B\uC740 \uBA74\uC5ED\uB2A5\uB825\uC774 \uC788\uB294 \uD658\uC790\uC640 \uBA74\uC5ED\uB825\uC774 \uC800\uD558\uB41C \uD658\uC790 \uBAA8\uB450\uC5D0\uC11C \uB0B4\uC131 \uADE0\uC8FC\uAC00 \uBD84\uB9AC\uB418\uC5C8\uB2E4. \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC5D0 \uB300\uD55C \uBBFC\uAC10\uC131\uACFC \uB0B4\uC131 \uBC14\uC774\uB7EC\uC2A4\uB4E4\uC758 \uC720\uBCD1\uB960\uC740 \uACC4\uC808\uC801\uC73C\uB85C, \uC9C0\uB9AC\uD559\uC801\uC73C\uB85C \uB2E4\uC591\uD558\uB2E4. \uB610\uD55C, \uC624\uC140\uD0C0\uBBF8\uBE44\uB974 \uB0B4\uC131\uC740 \uC720\uD589\uC131 H1N1 \uC778\uD50C\uB8E8\uC5D4\uC790\uB97C \uAC16\uACE0 \uC788\uB294 \uD658\uC790\uC758 \uCE58\uB8CC \uBC0F \uC608\uBC29 \uC694\uBC95 \uC911\uC5D0\uB3C4 \uBCF4\uACE0\uB41C \uBC14 \uC788\uB2E4.\r\n

<\/P>\uB0B4\uC131 \uBC1C\uD604\uC728\uC740 \uBA74\uC5ED\uB825\uC774 \uC800\uD558\uB41C \uD658\uC790\uC640 \uB9CC 12\uC138 \uBBF8\uB9CC\uC758 \uC18C\uC544\uC5D0\uC11C \uB192\uC744 \uC218 \uC788\uB2E4. \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uB97C \uD22C\uC57D\uD55C \uD658\uC790\uB85C\uBD80\uD130 \uBD84\uB9AC\uD55C \uC624\uC140\uD0C0\uBBF8\uBE44\uB974 \uB0B4\uC131 \uBC14\uC774\uB7EC\uC2A4\uC640 \uC624\uC140\uD0C0\uBBF8\uBE44\uB974 \uB0B4\uC131 \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4\uC758 \uC2E4\uD5D8\uC2E4 \uADE0\uC8FC\uC5D0\uC11C N1\uACFC N2 neuraminidases \uB3CC\uC5F0\uBCC0\uC774\uAC00 \uD3EC\uD568\uB41C \uAC83\uC774 \uAD00\uCC30\uB418\uC5C8\uB2E4. \uB0B4\uC131 \uB3CC\uC5F0\uBCC0\uC774\uB294 virus sub-type \uD2B9\uC774\uC801\uC778 \uACBD\uD5A5\uC774 \uC788\uB2E4.\r\n

<\/P>\uCC98\uBC29\uC758\uB294 \uC774 \uC57D\uC758 \uCC98\uBC29\uC744 \uACB0\uC815\uD560 \uB54C \uAC01 \uACC4\uC808\uBCC4 \uC778\uD50C\uB8E8\uC5D4\uC790 \uBC14\uC774\uB7EC\uC2A4 \uC57D\uBB3C \uBBFC\uAC10\uC131 \uD328\uD134\uC744 \uACE0\uB824\uD574\uC57C \uD55C\uB2E4.\r\n

<\/P>\r\n

<\/P>\r\n

<\/P>\r\n

<\/P>12. \uC758\uC57D\uD488\uB3D9\uB4F1\uC131\uC2DC\uD5D8 \uC815\uBCF4\uC8FC<\/SUP>1<\/SUP>\r\n

<\/P>\uAC00. \uC2DC\uD5D8\uC57D \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC778\uC0B0\uC5FC\uCEA1\uC29075\uBC00\uB9AC\uADF8\uB7A8[\uB300\uC6D0\uC81C\uC57D(\uC8FC)]\uC640 \uB300\uC870\uC57D \uD0C0\uBBF8\uD50C\uB8E8\uCEA1\uC29075\uBC00\uB9AC\uADF8\uB7A8(\uC778\uC0B0\uC624\uC140\uD0C0\uBBF8\uBE44\uB974)[(\uC8FC)\uD55C\uAD6D\uB85C\uC288]\uC744 2\u00D72 \uAD50\uCC28\uC2DC\uD5D8\uC73C\uB85C \uAC01 1\uCEA1\uC290\uC529 \uAC74\uAC15\uD55C \uC131\uC778\uC5D0\uAC8C \uACF5\uBCF5 \uC2DC \uB2E8\uD68C \uACBD\uAD6C\uD22C\uC5EC\uD558\uC5EC 56\uBA85\uC758 \uD608\uC911 \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uB97C \uCE21\uC815\uD55C \uACB0\uACFC, \uBE44\uAD50\uD3C9\uAC00\uD56D\uBAA9\uCE58(AUCt<\/SUB>, Cmax<\/SUB>)\uB97C \uB85C\uADF8\uBCC0\uD658\uD558\uC5EC \uD1B5\uACC4\uCC98\uB9AC\uD558\uC600\uC744 \uB54C, \uD3C9\uADE0\uCE58 \uCC28\uC758 90%\uC2E0\uB8B0\uAD6C\uAC04\uC774 log 0.8\uC5D0\uC11C log 1.25 \uC774\uB0B4\uB85C\uC11C \uC0DD\uBB3C\uD559\uC801\uC73C\uB85C \uB3D9\uB4F1\uD568\uC744 \uC785\uC99D\uD558\uC600\uB2E4.\r\n

<\/P>\r\n[&C5]\uB098. \uC758\uC57D\uD488\uB3D9\uB4F1\uC131\uC2DC\uD5D8\uAE30\uC900 \uC81C7\uC870\uC81C2\uD56D\uC5D0 \uB530\uB77C, \uC2DC\uD5D8\uC57D \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC778\uC0B0\uC5FC\uCEA1\uC29030\uBC00\uB9AC\uADF8\uB7A8 \uBC0F 45\uBC00\uB9AC\uADF8\uB7A8[\uB300\uC6D0\uC81C\uC57D(\uC8FC)]\uC740 \uB300\uC870\uC57D \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC778\uC0B0\uC5FC\uCEA1\uC29075\uBC00\uB9AC\uADF8\uB7A8[\uB300\uC6D0\uC81C\uC57D(\uC8FC)]\uACFC\uC758 \uBE44\uAD50\uC6A9\uCD9C\uC2DC\uD5D8\uC790\uB8CC\uB97C \uC81C\uCD9C\uD558\uC600\uC73C\uBA70, \uB300\uC870\uC57D\uACFC \uC6A9\uCD9C\uC591\uC0C1\uC774 \uB3D9\uB4F1\uD558\uC600\uB2E4. \uC774\uC5D0 \uB530\uB77C \uD574\uB2F9 \uC790\uB8CC\uB85C\uC11C \uC0DD\uBB3C\uD559\uC801\uB3D9\uB4F1\uC131\uC744 \uC785\uC99D\uD558\uC600\uB2E4.\r\n

<\/P>\uC8FC <\/SUP>1<\/SUP>. \uC774 \uC57D\uC740 \uB300\uC6D0\uC81C\uC57D(\uC8FC) \uC624\uC140\uD0C0\uBBF8\uBE44\uB974\uC778\uC0B0\uC5FC\uCEA1\uC290 30\uBC00\uB9AC\uADF8\uB7A8, 45\uBC00\uB9AC\uADF8\uB7A8 \uBC0F 75\uBC00\uB9AC\uADF8\uB7A8\uACFC \uB3D9\uC77C\uD55C \uC6D0\uB8CC\uB97C \uC0AC\uC6A9\uD558\uC5EC \uB3D9\uC77C\uD55C \uC81C\uC870\uBC29\uBC95\uC73C\uB85C \uC804 \uACF5\uC815\uC744 \uB300\uC6D0\uC81C\uC57D(\uC8FC)\uC5D0 \uC704\uD0C1 \uC81C\uC870\uD558\uC600\uC74C.\r\n

<\/P>","idfylength":"","boh":"\uC0AD\uC81C","etc":"","idfyidx":null,"reexam":null,"reexam_start_date":"","reexam_end_date":"","item_ingr_type":"1","additives":"\uC804\uD638\uD654\uC804\uBD84<\/br>\uCEA1\uC290<\/br>\uD06C\uB85C\uC2A4\uCE74\uB974\uBA5C\uB85C\uC624\uC2A4\uB098\uD2B8\uB968<\/br>\uD0E4\uD06C<\/br>\uD3EC\uBE44\uB3C8<\/br>\uD478\uB9C8\uB974\uC0B0\uC2A4\uD14C\uC544\uB9B4\uB098\uD2B8\uB968"}]